8-Chloro-1-(2,6-difluorophenyl)-3H-benzo[c]azepin-5(4H)-one CAS 869366-09-6
| CAS No. | 869366-09-6 |
| Molecular Formula | C16H10ClF2NO |
| Molecular Weight | 305.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 8-Chloro-1-(2,6-difluorophenyl)-3H-benzo[c]azepin-5(4H)-one (CAS 869366-09-6), a certified reference material (molecular formula C16H10ClF2NO, MW 305.71 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 8-Chloro-1-(2,6-difluorophenyl)-3H-benzo[c]azepin-5(4H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 305.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H10ClF2NO |
| Molecular Weight | 305.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-chloro-3-[(4-methoxybenzene)amido]benzoic acid (CAS 1030508-04-3)
- 1-(4-(4-Chloro-3-methylphenoxy)-3-nitrophenyl)ethanone (CAS 1036591-49-7)
- 4-(3-Chloro-5-trifluoromethyl-pyridin-2-yl)-2-methylsulfanyl-pyrimidine (CAS 1311279-25-0)
- 1365962-37-3 5-{[Chloro(phenyl)acetyl]amino}-2-hydroxybenzoic acid MFCD22056617 (CAS 1365962-37-3)
- Ethyl 2-(2-chloro-4-formylphenoxy)isonicotinate (CAS 1415719-37-7)
- Methyl 3-(2-chloro-4-methylphenyl)-5-nitrobenzoate (CAS 1820614-02-5)
- (E)-3-chloro-2-(2-(thiophen-2-ylmethylene)hydrazinyl)-5-(trifluoromethyl)pyridine (CAS 338795-24-7)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrole-2-carbothioamide (CAS 400080-85-5)
Recommended Standards
- 7-Chloro-N-[(2,5-difluorophenyl)methyl]quinazolin-4-amine (CAS 477870-06-7)
- Methyl 1-(2-(4-chlorophenyl)-2-oxoethyl)-2-oxo-1,2-dihydropyridine-3-carboxylate (CAS 339024-57-6)
- 7-Chloro-N-[(2,3-difluorophenyl)methyl]quinazolin-4-amine (CAS 477861-87-3)
- N-(5-Acetyl-6-methyl-2-oxo-2H-pyran-3-yl)-3-chlorobenzamide (CAS 339009-27-7)
- 4-chloro-6-nitrothieno[2,3-d]pyrimidine (CAS 56844-13-4)
- 3-(4-Bromothiophen-2-yl)prop-2-en-1-ol (CAS 1563672-39-8)
- 3-Cyclopropoxy-5-iodo-2-methoxypyridine (CAS 1243345-20-1)
- 2-Methyl-1,3,6-trioxocane (CAS 2781-01-3)
- (4-Aminophenyl)(tert-butylimino)(methyl)-l6-sulfanone (CAS 2616728-04-0)
- N,N-dibutyl-N-ethylbutan-1-aminium ethyl sulfate (CAS 68052-51-7)
- (2E)-3-(Dimethylamino)-1-(4-phenoxyphenyl)prop-2-en-1-one (CAS 241488-13-1)
- 7-Methyl-2,3-dihydro-1H-inden-4-ol (CAS 16400-13-8)
- Methyl 3-(3-amino-1h-pyrazol-1-yl)-2,2-dimethylpropanoate (CAS 1506347-15-4)
- C-Peptide 2 (rat) (CAS 41594-08-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com