N-[4-Amino-5-(2,3-difluoro-6-methoxybenzoyl)-2-pyrimidinyl]-1-(methylsulfonyl)-4-piperidinamine monomethanesulfonate CAS 869369-26-6
| CAS No. | 869369-26-6 |
| Molecular Formula | C18H21F2N5O4S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-[4-Amino-5-(2,3-difluoro-6-methoxybenzoyl)-2-pyrimidinyl]-1-(methylsulfonyl)-4-piperidinamine monomethanesulfonate is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-[4-Amino-5-(2,3-difluoro-6-methoxybenzoyl)-2-pyrimidinyl]-1-(methylsulfonyl)-4-piperidinamine monomethanesulfonate (CAS 869369-26-6), molecular formula C18H21F2N5O4SCH4O3S and molecular weight 537.55 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-[4-Amino-5-(2,3-difluoro-6-methoxybenzoyl)-2-pyrimidinyl]-1-(methylsulfonyl)-4-piperidinamine monomethanesulfonate (C18H21F2N5O4SCH4O3S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-[4-Amino-5-(2,3-difluoro-6-methoxybenzoyl)-2-pyrimidinyl]-1-(methylsulfonyl)-4-piperidinamine monomethanesulfonate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H21F2N5O4S CH4O3S |
| Molecular Weight | 537.55 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related N Standards
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- Methyl 2-amino-5-bromo-4-isopropylbenzoate (CAS 1000018-13-2)
- Methyl 2-amino-3-(pyridin-2-yl)propanoate (CAS 100002-84-4)
- 100005-23-0 2-Amino-4-(4-methoxyphenyl)-5-methylthiophene-3-carbonitrile 7050AC C13H12N2OS (CAS 100005-23-0)
- Methyl 1-amino-4-cyano-1H-pyrrole-2-carboxylate (CAS 1000313-12-1)
- 6-Amino-7-hydroxy-2,3-dihydro-1H-inden-1-one hydrobromide (CAS 1000333-87-8)
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Recommended Standards
- 2-(Benzyloxy)-3,5-dichlorobenzaldehyde (CAS 40359-57-7)
- Methyl 6-chloro-3-methoxypicolinate (CAS 175965-90-9)
- Oxazolo[4,5-c]pyridin-4-amine (CAS 607366-45-0)
- 3-(Pyrrolidin-1-yl)pyridin-2-amine (CAS 1286273-39-9)
- Losartan Impurity 49 (CAS CATO-C4X-168349)
- (4-Chloro-2-(1-oxo-1,3,4,6,7,8,9,10-octahydro-2H-cyclohepta[4,5]pyrrolo[1,2-a]pyrazin-2-yl)pyridin-3-yl)methyl acetate (CAS 2387599-99-5)
- 3-Formyl-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylic acid (CAS 1252672-30-2)
- 2-bromo-1-(3,4-difluoro-2-hydroxyphenyl)ethan-1-one (CAS 1621375-69-6)
- 2-Ethyl-5,6-dimethylthieno[2,3-d]pyrimidine-4-thiol (CAS 917746-80-6)
- Lixisenatide (CAS 320367-13-3)
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