trans-3,4-Difluoropyrrolidine CAS 869532-49-0
| CAS No. | 869532-49-0 |
| Molecular Formula | C4H7F2N |
| Molecular Weight | 107.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to fluorine substitution, trans-3,4-Difluoropyrrolidine is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 107.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies trans-3,4-Difluoropyrrolidine (CAS 869532-49-0), a certified reference material (molecular formula C4H7F2N, MW 107.10 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), trans-3,4-Difluoropyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H7F2N |
| Molecular Weight | 107.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related trans Standards
- 3,4-Difluoropyrrolidine (CAS 1144062-04-3)
- 3,3-Difluoropyrrolidine (CAS 316131-01-8)
- cis-3,4-Difluoropyrrolidine (CAS 869532-50-3)
- (R)-4,4-difluoropyrrolidine-2-carbonitrile (CAS 1613482-35-1)
- 4,4-Difluoropyrrolidine-3-carbonitrile (CAS 1780714-82-0)
- (S)-4,4-difluoropyrrolidine-2-carbonitrile (CAS 483366-15-0)
- (S)-4,4-Difluoropyrrolidine-2-carbaldehyde (CAS 1357281-62-9)
- (R)-4,4-Difluoropyrrolidine-2-carbaldehyde (CAS 2277300-69-1)
Recommended Standards
- L-Serine-3,3-d2 (CAS 95034-57-4)
- 5-Methylimidazole-4-carbonitrile (CAS 108257-41-6)
- 1H-Imidazole-5-carbonitrile, 2-methyl- (CAS 112108-86-8)
- 2-Pyrazol-1-ylacetonitrile (CAS 113336-22-4)
- 1-(2-Ethyl-1,3-thiazol-5-yl)methanamine (CAS 1183523-89-8)
- 5-tert-Butyl-2-piperidin-1-ylmethyl-furan-3-carboxylic acid hydrochloride (CAS 435342-03-3)
- 6-Bromo-2-methoxypyridine-3-sulfonyl chloride (CAS 1261866-85-6)
- 2-Bromo-5-chloro-3-(trifluoromethyl)acetophenone (CAS 1805591-24-5)
- 5-Ethyl-3-(methylthio)pyridin-2-amine (CAS 2794196-98-6)
- Rimegepant Impurity 146 (CAS CATO-C4X-2487146)
- L-Proline tert-Butyl Ester Hydrochloride (CAS 5497-76-7)
- (1-Allylpiperidin-4-yl)methanol (CAS 101966-71-6)
- 3-(4-Chlorophenyl)-2,2-dimethylpropanoic acid (CAS 57145-14-9)
- Serpent Peptide 2AcOH (CAS 823202-99-9(free base))
Why CATO?
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