Methyl 2-fluoro-2-(4-oxo-3,4-dihydroquinazolin-2-yl)acetate CAS 869634-05-9
| CAS No. | 869634-05-9 |
| Molecular Formula | C11H9FN2O3 |
| Molecular Weight | 236.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 2-fluoro-2-(4-oxo-3,4-dihydroquinazolin-2-yl)acetate (CAS 869634-05-9), molecular formula C11H9FN2O3 and molecular weight 236.20 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Methyl 2-fluoro-2-(4-oxo-3,4-dihydroquinazolin-2-yl)acetate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9FN2O3 |
| Molecular Weight | 236.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
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Recommended Standards
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- (R)-2-Amino-3-(quinolin-3-yl)propanoic acid (CAS 135213-89-7)
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- 4-Bromo-1-isopropyl-3-(trifluoromethyl)-1H-pyrazole (CAS 1426958-33-9)
- Tris(2-cyclohexylethyl)(phenyl)silane (CAS 18758-76-4)
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