1-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-amine CAS 869747-17-1
| CAS No. | 869747-17-1 |
| Molecular Formula | C12H15F3N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-amine.
1-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-amine (CAS 869747-17-1), molecular formula C12H15F3N2HCl and molecular weight 280.72 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-amine (C12H15F3N2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15F3N2 2*HCl |
| Molecular Weight | 280.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related trifluoromethyl Standards
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-ol hydrochloride (CAS 1000198-74-2)
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1000198-76-4)
- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1000339-72-9)
- methyl 3-((4-(trifluoromethyl)piperidin-1-yl)methyl)benzoate (CAS 1000339-86-5)
- methyl 4-(2-(4-(trifluoromethyl)piperidin-1-yl)ethoxy)benzoate (CAS 1000339-87-6)
- 2-(4-(trifluoromethyl)piperidin-1-yl)thiazole-5-carbaldehyde (CAS 1000339-88-7)
- 3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)benzaldehyde (CAS 1000339-89-8)
- 4-(2-(4-(trifluoromethyl)piperidin-1-yl)acetyl)-1H-pyrrole-2-carbaldehyde (CAS 1000339-90-1)
Recommended Standards
- 3-Methyl-1-phenyl-1H-pyrazole-4,5-diamine (CAS 52943-88-1)
- ((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3-ethoxy-4-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 97130-90-0)
- (2R,3R)-1-((benzyloxy)carbonyl)-3-hydroxypyrrolidine-2-carboxylic acid (CAS 1215291-99-8)
- Ethyl 2-(pyridin-2-ylthio)acetate (CAS 28856-92-0)
- N-(pyridin-3-ylmethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide hydrochloride (CAS 1220038-55-0)
- 3,8,9-Triazatricyclo[4.3.0.02,5]nonane (CAS 105666-13-5)
- 2-(Aminomethyl)-3-chloro-4-(difluoromethyl)-5-fluoropyridine (CAS 1805985-17-4)
- 2-(Thiophen-2-yl)acetohydrazide (CAS 39978-18-2)
- (S)-5-Bromo-2,3-dihydrospiro[indene-1,5'-oxazolidine]-2',4'-dione (CAS 1889291-77-3)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
Why CATO?
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