4-(2,2,2-Trifluoroacetyl)benzaldehyde CAS 86988-50-3
| CAS No. | 86988-50-3 |
| Molecular Formula | C9H5F3O2 |
| Molecular Weight | 202.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(2,2,2-Trifluoroacetyl)benzaldehyde (CAS 86988-50-3), molecular formula C9H5F3O2 and molecular weight 202.13 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 4-(2,2,2-Trifluoroacetyl)benzaldehyde is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 202.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(2,2,2-Trifluoroacetyl)benzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5F3O2 |
| Molecular Weight | 202.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F-containing |
Related Trifluoroacetyl Standards
- 1-Trifluoroacetyl-4-methylthiosemicarbazide (CAS 25366-21-6)
- (2,2,2-Trifluoroacetyl)serine (CAS 848860-96-8)
- N-(trifluoroacetyl)-Alanyl Chloride (CAS 1597-19-9)
- N-trifluoroacetyl-β-alanyl chloride (CAS 87639-76-7)
- 2-(2,2,2-Trifluoroacetyl)nicotinonitrile (CAS 1060802-66-5)
- 6-(2,2,2-Trifluoroacetyl)pyridine-3-carbonitrile (CAS 1060804-08-1)
- 5-(2,2,2-Trifluoroacetyl)nicotinonitrile (CAS 1060804-10-5)
- 4-(2,2,2-Trifluoroacetyl)nicotinonitrile (CAS 1060804-11-6)
Recommended Standards
- 3-Methyl-4-(trifluoromethoxy)picolinonitrile (CAS 886372-31-2)
- 4-(Trifluoromethyl)benzo[d]isoxazol-3-amine (CAS 229623-54-5)
- 3-Methoxy-5-(trifluoromethyl)picolinonitrile (CAS 400085-19-0)
- 4-Amino-2-(trifluoromethoxy)benzonitrile (CAS 609783-06-4)
- 4-(4-Methyl-1-piperazinyl)benzaldehyde Hydrochloride (CAS 1424939-17-2)
- Hemiphroside B (CAS 165338-28-3)
- 6-Chloro-4-methoxy-2-methyl-1H-benzo[d]imidazole (CAS 1935370-54-9)
- 3-Heptyl-2-thioxo-1,3-thiazolidin-4-one (CAS 39137-05-8)
- 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-dione (CAS 103979-54-0)
- Pentane-1,5-diylbis(triphenylphosphonium) bromide (CAS 22884-31-7)
- Indacaterol impurity 84 (CAS CATO-C4X-150084)
- Pyridine-2-boronic Acid Pinacol Ester (CAS 874186-98-8)
- 2-(Difluoromethyl)-3,4-dihydroxypyridine-6-acetonitrile (CAS 1806818-84-7)
- Protein Kinase C (19-36) Peptide (CAS 113731-96-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com