5-Chloro-4-iodo-N-isopropylpyridin-2-amine CAS 869886-87-3
| CAS No. | 869886-87-3 |
| Molecular Formula | C8H10ClIN2 |
| Molecular Weight | 296.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Chloro-4-iodo-N-isopropylpyridin-2-amine (CAS 869886-87-3), molecular formula C8H10ClIN2 and molecular weight 296.54 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution, 5-Chloro-4-iodo-N-isopropylpyridin-2-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 296.54 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H10ClIN2 |
| Molecular Weight | 296.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-5-iodo-N-isopropylpyridin-4-amine (CAS 1447227-69-1)
- 4-chloro-5-iodo-6-(2-methylpropyl)pyrimidine (CAS 1514650-08-8)
- 4-Chloro-5-iodo-2-isopropyl-6-methylpyrimidine (CAS 69696-39-5)
- 2-(7-Chloro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2235368-22-4)
- 3-Chloro-2-methoxycarbonylphenylboronic acid, pinacol ester (CAS 1980783-96-7)
- Methyl 2-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 2201133-24-4)
- Methyl 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 334018-52-9)
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- 2-(2-(1H-Imidazol-5-yl)ethyl)isoindoline-1,3-dione (CAS 5959-80-8)
- Ethyl 2-(4-chloro-3-methyl-1H-pyrazol-1-yl)butanoate (CAS 1171381-25-1)
- 5-acetyl-6-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one (CAS 90151-12-5)
- Methyl 5-ethynylpyrimidine-2-carboxylate (CAS 1196153-35-1)
- 1-Propyl-1h-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 130574-89-9)
- 3-Hydroxy-2-(methylsulfonamido)benzenesulfonamide (CAS 1243476-55-2)
- Tirzepatide Impurity 50 (CAS CATO-C4X-324050)
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