4-Cyclopropyl-2-hydroxy-6-(trifluoromethyl)nicotinonitrile CAS 869947-05-7

Purity 97%+In StockPharmaceutical Standards
CAS No.869947-05-7
Molecular FormulaC10H7F3N2O
Molecular Weight228.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Cyclopropyl-2-hydroxy-6-(trifluoromethyl)nicotinonitrile CAS 869947-05-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 228.17 g/mol gives 4-Cyclopropyl-2-hydroxy-6-(trifluoromethyl)nicotinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-Cyclopropyl-2-hydroxy-6-(trifluoromethyl)nicotinonitrile (CAS 869947-05-7), molecular formula C10H7F3N2O and molecular weight 228.17 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-Cyclopropyl-2-hydroxy-6-(trifluoromethyl)nicotinonitrile is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 228.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-Cyclopropyl-2-hydroxy-6-(trifluoromethyl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H7F3N2O
Molecular Weight228.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms2

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