4,4,4-Trifluoro-3-hydroxy-3-(1-methyl-1H-imidazol-2-yl)butanoic Acid CAS 871478-30-7
| CAS No. | 871478-30-7 |
| Molecular Formula | C8H9F3N2O3 |
| Molecular Weight | 238.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,4,4-Trifluoro-3-hydroxy-3-(1-methyl-1H-imidazol-2-yl)butanoic Acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4,4,4-Trifluoro-3-hydroxy-3-(1-methyl-1H-imidazol-2-yl)butanoic Acid (CAS 871478-30-7), a certified reference material (molecular formula C8H9F3N2O3, MW 238.16 g/mol) for analytical method development and quality control.
4,4,4-Trifluoro-3-hydroxy-3-(1-methyl-1H-imidazol-2-yl)butanoic Acid (C8H9F3N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4,4,4-Trifluoro-3-hydroxy-3-(1-methyl-1H-imidazol-2-yl)butanoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9F3N2O3 |
| Molecular Weight | 238.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoro Standards
- 1-(4,4,4-Trifluoro-3-hydroxybutyl)-1H-pyrazole-5-carboxylic acid (CAS 2549160-47-4)
- 1-Methyl-3-(2,2,2-trifluoro-1-methoxyethyl)-1H-pyrazole-5-carboxylic acid (CAS 2821786-27-8)
- 4,4,4-Trifluoro-3-hydroxy-3-(5-methylfuran-2-yl)butanoic acid (CAS 929974-43-6)
- 2,2,2-trifluoro-1-(2-fluoro-3-nitrophenyl)ethan-1-amine (CAS 1391302-88-7)
- 3,3,3-Trifluoro-2-(4-fluorophenyl)-2-hydroxypropanoic acid (CAS 1541985-06-1)
- 3,3,3-Trifluoro-2-(3-fluorophenyl)-2-hydroxypropanoic acid (CAS 1544848-23-8)
- Ethyl 4,4,4-trifluoro-3-(trifluoromethyl)butanoate (CAS 17327-34-3)
- 2,2,2-Trifluoro-1-(2-methylnaphthalen-1-yl)ethanone (CAS 131831-98-6)
Recommended Standards
- 1-Ethyl-4-(2,2,2-trifluoroethoxy)-1H-pyrazole-3-carboxylic acid (CAS 2394876-76-5)
- Bis(4-nitro-1h-pyrazol-1-yl)methane (CAS 86111-62-8)
- Ethyl (R)-5-methyl-4-oxo-5-(trifluoromethyl)-4,5-dihydrofuran-2-carboxylate (CAS 2878423-90-4)
- 1-(2-Methoxyethyl)-5-(trifluoromethyl)-1h-pyrazole-3-carboxylic acid (CAS 2092336-57-5)
- endo-3-Aminomethyl-8-boc-8-azabicyclo[3.2.1]octane (CAS 273376-40-2)
- D-galactosamine-1- (CAS 478518-54-6)
- 1-Allylcyclopropylsulfonamide (CAS 669008-28-0)
- tert-Butyl (2S,4S)-4-(((benzyloxy)carbonyl)amino)-2-(cyanomethyl)piperidine-1-carboxylate (CAS 2667055-47-0)
- (3AS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-3a-((prop-2-yn-1-yloxy)methyl)tetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran (CAS 364733-08-4)
- tert-Butyl 4-(2-bromo-5-methoxybenzyl)piperazine-1-carboxylate (CAS 339152-01-1)
- 3-Amino-1,2-dihydroxyanthracene-9,10-dione (CAS 3963-78-8)
- 2-Amino-6-(difluoromethyl)-5-formylnicotinonitrile (CAS 1805212-71-8)
- RSS0343 Impurity 2 (CAS CATO-C4X-32722)
- Polymyxin B nonapeptide (CAS 86408-36-8)
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