1,5-Dioxo-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1H)-carboxylic acid CAS 871909-89-6
| CAS No. | 871909-89-6 |
| Molecular Formula | C12H10N2O4 |
| Molecular Weight | 246.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 246.22 g/mol gives 1,5-Dioxo-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1H)-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1,5-Dioxo-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1H)-carboxylic acid (CAS 871909-89-6), molecular formula C12H10N2O4 and molecular weight 246.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1,5-Dioxo-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1H)-carboxylic acid (C12H10N2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1,5-Dioxo-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1H)-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10N2O4 |
| Molecular Weight | 246.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 1-(5-Methyl-3-(3-nitrophenyl)-1H-1,2,4-triazol-1-yl)ethan-1-one (CAS 61598-91-2)
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- 1-(4-Methoxyphenyl)-4-oxo-1,4-dihydropyridazine-3-carboxylic acid (CAS 478077-66-6)
- 1-Benzyl-6-hydroxy-2-oxo-1,2-dihydropyrimidine-4-carboxylic acid (CAS 338774-89-3)
- 7-chloro-3-iodo-1H-pyrrolo[3,2-b]pyridine (CAS 1190318-10-5)
- 5-Methoxy-1-naphthoic Acid (CAS 51934-37-3)
- 2-Bromo-6-(furan-2-ylmethoxy)pyridine (CAS 1065484-89-0)
- (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-cyclobutylpropanoic acid (CAS 1260605-23-9)
- 1,3-Dichloro-5-fluoroisoquinoline (CAS 1259223-98-7)
- 1-(4-Methoxybenzyl)-3,5-dimethyl-1h-pyrazole-4-carboxylic acid (CAS 1022989-64-5)
- Linagliptin Impurity 75 (CAS 14785-95-6)
- 6-(2,6-Difluorophenyl)pyridazin-3-amine (CAS 1250246-22-0)
- tert-Butyl (2-(5-acetyl-4-hydroxypyridin-2-yl)ethyl)carbamate (CAS 1393551-78-4)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
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