(2,5-Difluoro-4-methylphenyl)boronic acid CAS 872219-20-0
| CAS No. | 872219-20-0 |
| Molecular Formula | C7H7BF2O2 |
| Molecular Weight | 171.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (2,5-Difluoro-4-methylphenyl)boronic acid (C7H7BF2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies (2,5-Difluoro-4-methylphenyl)boronic acid (CAS 872219-20-0), a certified reference material (molecular formula C7H7BF2O2, MW 171.94 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7BF2O2 |
| Molecular Weight | 171.94 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Difluoro Standards
- (4,5-Difluoro-2-methylphenyl)boronic acid (CAS 1416244-48-8)
- 2,6-Difluoro-3-methylphenylboronic acid (CAS 1586045-40-0)
- (2,4-Difluoro-3-methylphenyl)boronic acid (CAS 1619980-13-0)
- 3,5-Difluoro-4-methylphenylboronic Acid (CAS 1621332-09-9)
- (3,6-Difluoro-2-methylphenyl)boronic acid (CAS 1884277-68-2)
- (2,4-Difluoro-5-methylphenyl)boronic acid (CAS 900175-09-9)
- 2,3-Difluoro-4-methylphenylboronic acid (CAS 508235-16-3)
- 2,3-Difluoro-5-methylphenylboronic acid (CAS 934247-79-7)
Recommended Standards
- [(2,6-Difluorophenyl)methyl]boronic acid (CAS 2246550-95-6)
- (2-(Difluoromethyl)phenyl)boronic acid (CAS 879275-70-4)
- [(3,4-Difluorophenyl)methyl]boronic acid (CAS 2246751-44-8)
- 2,6-Difluoro-4-methylphenylboronic acid (CAS 2246867-26-3)
- Pyrazolidine-3,5-dione (CAS 4744-71-2)
- (E)-4-(4-benzylpiperazin-1-yl)-4-oxobut-2-enoic acid (CAS 304684-78-4)
- 5-Bromo-2-fluorothiazole (CAS 1207608-60-3)
- Tirofiban Chloro Impurity (CAS CATO-C4X-125425)
- 2-Diethoxymethyl-1,1-diethoxybutane (CAS 30989-69-6)
- cis-2-Methylhexahydropyrrolo[3,4-c]pyrrole (CAS 172739-03-6)
- 3-(Difluoromethoxy)tetrahydro-4H-pyran-4-one (CAS 2141137-50-8)
- 3-Iodobenzaldehyde (CAS 696-41-3)
- (3S,4S)-3-methoxypiperidin-4-ol (CAS 1612172-94-7)
- Insulin Detemir (CAS 169148-63-4)
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