2-(Chloromethyl)-6-fluoroimidazo[1,2-a]pyridine CAS 872363-18-3
| CAS No. | 872363-18-3 |
| Molecular Formula | C8H6ClFN2 |
| Molecular Weight | 184.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(Chloromethyl)-6-fluoroimidazo[1,2-a]pyridine (CAS 872363-18-3) is a high-purity analytical reference standard with the molecular formula C8H6ClFN2 and a molecular weight of 184.60 g/mol.
Based on its molecular formula C8H6ClFN2, 2-(Chloromethyl)-6-fluoroimidazo[1,2-a]pyridine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 184.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-(Chloromethyl)-6-fluoroimidazo[1,2-a]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClFN2 |
| Molecular Weight | 184.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloromethyl Standards
- 3-(Chloromethyl)-6-fluoroimidazo[1,2-a]pyridine (CAS 1019023-48-3)
- 3-(Chloromethyl)-5-fluoro-1H-indazole (CAS 1196156-02-1)
- 5-(Chloromethyl)-6-fluoro-1H-indazole (CAS 1360978-88-6)
- 2-(Chloromethyl)-6-fluoro-1H-benzo[d]imidazole (CAS 156144-42-2)
- 2-(Chloromethyl)-4-fluoro-1H-benzo[d]imidazole (CAS 405173-94-6)
- 2-(Chloromethyl)-5-fluoroimidazo[1,2-a]pyridine (CAS 878198-71-1)
- 2-(Chloromethyl)-5-(difluoromethyl)-1,3,4-thiadiazole (CAS 1443982-10-2)
- 3-(Chloromethyl)-5-fluorobenzofuran (CAS 252978-98-6)
Recommended Standards
- 2-chloro-5-fluoro-1-methyl-1H-1,3-benzodiazole (CAS 401567-12-2)
- 2-chloro-6-fluoro-1-methyl-1H-1,3-benzodiazole (CAS 348133-47-1)
- 2-(Chlorofluoromethyl)-1H-benzo[d]imidazole (CAS 73774-29-5)
- 2-oxooxolane-3-sulfonyl chloride (CAS 40336-84-3)
- 4-Chloro-3-fluoro-4-methoxybenzophenone (CAS 760192-86-7)
- 2-(6-(tert-Butyl)-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzaldehyde (CAS 1242156-60-0)
- 2-Amino-6-(bromomethyl)benzoic acid (CAS 632340-58-0)
- Thiophene-2,5-diylbis(methylene) dicarbamimidothioate dihydrochloride (CAS 2076-91-7)
- N-(6-Bromo-1-nitro-2-naphthyl)acetamide (CAS 855930-17-5)
- 2,4,6-Tris(trichloromethyl)-1,3,5-triazine (CAS 6542-67-2)
- N-(4-Chlorobenzyl)quinazolin-4-amine (CAS 70137-93-8)
- (R)-2-(2-Acetylphenyl)-2-hydroxyacetic acid (CAS 915971-32-3)
- Ethyl 5-(2-acetoxyethyl)-4-methylthiophene-3-carboxylate (CAS 19156-47-9)
- 1-His-N-a-ethylidene Semaglutide (CAS CATO-C4X-2226252)
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