2-Iodo-4-methyl-5-(trifluoromethyl)aniline CAS 872624-68-5
| CAS No. | 872624-68-5 |
| Molecular Formula | C8H7F3IN |
| Molecular Weight | 301.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Iodo-4-methyl-5-(trifluoromethyl)aniline (CAS 872624-68-5), a certified reference material (molecular formula C8H7F3IN, MW 301.05 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution, 2-Iodo-4-methyl-5-(trifluoromethyl)aniline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 301.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Iodo-4-methyl-5-(trifluoromethyl)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7F3IN |
| Molecular Weight | 301.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- (2-Iodo-5-(trifluoromethyl)phenyl)methanamine (CAS 1261612-96-7)
- (3-Iodo-2-(trifluoromethyl)phenyl)methanamine (CAS 1261682-41-0)
- (2-Iodo-3-(trifluoromethyl)phenyl)methanamine (CAS 1261762-01-9)
- 3-Iodo-4-(trifluoromethyl)benzylamine (CAS 1261827-19-3)
- 4-Iodo-2-methyl-5-(trifluoromethyl)aniline (CAS 1823313-66-1)
- (3-Iodo-5-(trifluoromethyl)phenyl)methanamine (CAS 691877-06-2)
- 2-Iodo-3-methyl-5-(trifluoromethyl)aniline (CAS 2055274-65-0)
- 6-Iodo-7-nitroquinoxaline (CAS 113269-14-0)
Recommended Standards
- 948290-77-5 6-Bromo-2-chloro-3-(chloromethyl)quinoline DTXSID20588976 (CAS 948290-77-5)
- 948291-25-6 7-Bromo-2-chloro-3-(chloromethyl)quinoline DTXSID90588983 (CAS 948291-25-6)
- 3-[4-bromo-5-methyl-3-(trifluoromethyl)-1h-pyrazol-1-yl]propanoic acid (CAS 1001518-85-9)
- (3-Bromo-4-fluorophenyl)pentafluoro-lambda6-sulfane (CAS 1706434-97-0)
- 4,4'-(Naphthalene-1,4-diyl)bis(1-(4-isopropylphenyl)pyridin-1-ium)chloride (CAS 2380279-77-4)
- (±)-Linalool-d3 (vinyl-d3) (CAS 1216673-02-7)
- 1-(2,6-Dimethylpyrimidin-4-yl)methanamine (CAS 870516-92-0)
- Azide-PEG3-Sulfone-PEG3-azide (CAS 2055024-45-6)
- 2-(Hydroxymethyl)benzo[d]oxazole-6-carboxamide (CAS 1804203-57-3)
- Methyl 3-{[2-(4-fluorophenyl)ethyl]amino}-2-methylpropanoate (CAS 1154155-88-0)
- 2-Amino-4-chloro-3-fluoro-5-(trifluoromethyl)benzoic acid (CAS 1698027-64-3)
- Docetaxel Impurity 18 (CAS 146924-94-9)
- (R)-2-amino-2-(quinolin-7-yl)ethan-1-ol (CAS 1213567-42-0)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
Why CATO?
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