3'-(Trifluoromethoxy)-[1,1'-biphenyl]-2-amine CAS 873056-54-3
| CAS No. | 873056-54-3 |
| Molecular Formula | C13H10F3NO |
| Molecular Weight | 253.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3'-(Trifluoromethoxy)-[1,1'-biphenyl]-2-amine (CAS 873056-54-3), molecular formula C13H10F3NO and molecular weight 253.22 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3'-(Trifluoromethoxy)-[1,1'-biphenyl]-2-amine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 253.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 3'-(Trifluoromethoxy)-[1,1'-biphenyl]-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10F3NO |
| Molecular Weight | 253.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethoxy Standards
- 5-Methyl-2-(4-(trifluoromethoxy)phenyl)pyridine (CAS 1261767-88-7)
- 2'-(Trifluoromethoxy)-[1,1'-biphenyl]-2-amine (CAS 175676-54-7)
- 3-[2-(trifluoromethoxy)phenyl]aniline (CAS 764704-38-3)
- 4'-(Trifluoromethoxy)-[1,1'-biphenyl]-2-amine (CAS 728919-15-1)
- 4'-(Trifluoromethoxy)-[1,1'-biphenyl]-3-amine (CAS 436150-22-0)
- 4'-(Trifluoromethoxy)-[1,1'-biphenyl]-4-amine (CAS 728919-14-0)
- 4-(Trifluoromethoxy)-1,4'-bipiperidine (CAS 2306272-63-7)
- 4-[4-(Trifluoromethoxy)phenyl]-1H-1,2,3-triazole-5-carbonitrile (CAS 1020252-27-0)
Recommended Standards
- 3-(4-(Trifluoromethyl)phenoxy)aniline (CAS 78748-23-9)
- 3'-(Trifluoromethyl)-3,6-dihydro-2H-[1,2'-bipyridine]-4-carbonitrile (CAS 801306-56-9)
- 2,5-dimethyl-1-(2,3,4-trifluorophenyl)-1H-pyrrole-3-carbaldehyde (CAS 923832-17-1)
- 3-(trifluoromethyl)thieno[3,2-d][1,2]thiazole-5-carboxylic acid (CAS 2091593-71-2)
- 4-Amino-1-(3-pyridinyl)cyclohexanol (CAS 1509382-54-0)
- (S)-3-([1,1'-biphenyl]-2-yl)-2-(((tert-butoxycarbonyl)amino)methyl)propanoic acid (CAS 1260603-51-7)
- 5-Fluoro-2-methylphenylhydrazine (CAS 2339-53-9)
- Orforglipron Impurity 146 (CAS CATO-C4X-3234146)
- 2-(4-Bromophenyl)-3-methylbutanenitrile (CAS 51632-12-3)
- 5-(4-Fluorophenyl)pyrimidine (CAS 68049-21-8)
- 4-(4-Azidophenyl)butyric acid (CAS 103489-33-4)
- (E)-[(4-Chlorophenyl)methylidene]amino 4-tert-butylbenzoate (CAS 331462-08-9)
- Benzyl 2-(((2-aminoethyl)(cyclopropyl)amino)methyl)pyrrolidine-1-carboxylate (CAS 1353953-52-2)
- [γ-Glu]15 Semaglutide (CAS CATO-C4X-222690)
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