(R)-1-Benzyl-3-fluoropiperidine CAS 873221-82-0
| CAS No. | 873221-82-0 |
| Molecular Formula | C12H16FN |
| Molecular Weight | 193.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 193.26 g/mol gives (R)-1-Benzyl-3-fluoropiperidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(R)-1-Benzyl-3-fluoropiperidine (CAS 873221-82-0), molecular formula C12H16FN and molecular weight 193.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (R)-1-Benzyl-3-fluoropiperidine (C12H16FN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (R)-1-Benzyl-3-fluoropiperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16FN |
| Molecular Weight | 193.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (1-Methanesulfonylpiperidin-3-yl)methanol (CAS 349403-27-6)
- (R)-3-(4-Fluorobenzyl)piperidine (CAS 794464-41-8)
- (1-Methanesulfonylpiperidin-2-yl)methanol (CAS 349403-28-7)
- (S)-(1-Methylpyrrolidin-2-yl)methyl methanesulfonate (CAS 607370-14-9)
- 2-(2-Piperazinyl)ethanol Dihydrochloride (CAS 5169-93-7)
- 1233AF 4-(3-Methoxyphenyl)-1-methylpiperidine-4-carboxylic acid 874532-98-6 C14H19NO3 (CAS 874532-98-6)
- 1,1-Dimethylbutyl 2-methyl-2-propenoate (CAS 100472-88-6)
- Tert-butyl 4-(6-bromo-1H-benzo[d]imidazol-1-yl)azepane-1-carboxylate (CAS 1251017-58-9)
- (3-((Naphthalen-2-yloxy)methyl)-1,2,4-oxadiazol-5-yl)methanamine hydrochloride (CAS 1235097-48-9)
- 1-Benzyl-3-ethylpyrrolidin-3-amine (CAS 914916-20-4)
- 1-(pyridin-2-yl)-N-((tetrahydrofuran-2-yl)methyl)methanamine 202199-02-8 Pyridin-2-ylmehyl-(tetrahydrofuran-2-ylmethyl)amine (CAS 202199-02-8)
- (5Z)-5-[(4-Heptylphenyl)methylidene]-1,3-thiazolidine-2,4-dione (CAS 477856-75-0)
- ethyl 5-formylfuran-3-carboxylate (CAS 32365-53-0)
- Semaglutide Impurity 164 (CAS CATO-C4X-2226164)
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