rac-Atomoxetine EP Impurity D HCl CAS 873310-28-2
| CAS No. | 873310-28-2 |
| Molecular Formula | C17H21NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 291.82 g/mol gives rac-Atomoxetine EP Impurity D HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies rac-Atomoxetine EP Impurity D HCl (CAS 873310-28-2), a pharmacopoeial impurity reference standard (molecular formula C17H21NOHCl, MW 291.82 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, rac-Atomoxetine EP Impurity D HCl is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 291.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H21NO HCl |
| Molecular Weight | 291.82 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related rac Standards
- Atomoxetine Impurity 50 (CAS 1007832-68-9)
- Atomoxetine impurity 40 (CAS 1010818-92-4)
- Atomoxetine impurity 41 (CAS 1010818-92-4（free base）)
- Atomoxetine EP Impurity C (CAS 1010818-96-8)
- Atomoxetine Impurity 9 HCl (CAS 1011-59-2)
- Atomoxetine EP impurity B (CAS 105314-53-2)
- Atomoxetine impurity 01 (CAS 109306-10-7)
- Atomoxetine EP Impurity H (S-Isomer) (CAS 114133-37-8)
Recommended Standards
- Nateglinide EP Impurity A (CAS 7077-05-6)
- Metformin EP impurity F Tetrahydrofuran Solution (CAS 124-40-3 (free base))
- Avibactam Impurity 37 (CAS CATO-C4X-134837)
- Potassium bis(2-hydroxyethyl)sulfamate (CAS 210306-72-2)
- N-{2-[2-(2-Aminoethoxy)-ethoxy]-ethyl}-4-sulfamoylbenzamide (CAS 165618-72-4)
- (E)-5-(2-((4-bromophenyl)amino)vinyl)-3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)isothiazole-4-carbonitrile (CAS 338412-99-0)
- N-(2-(4-hydroxypiperidin-1-yl)ethyl)-N-methylnitrous amide (CAS CATO-C4X-239922)
- N-(2-(2-Phenylpyrimidin-5-yl)ethyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide (CAS 2034512-92-8)
- 6-Bromo-7-methylquinoline-4-carboxylic acid (CAS 2791473-98-6)
- Peptide 432 (CAS CATO-CPTD788432)
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