8-[(6-Iodobenzo[d][1,3]dioxol-5-yl)thio]-9H-purin-6-amine CAS 873436-89-6
| CAS No. | 873436-89-6 |
| Molecular Formula | C12H8IN5O2S |
| Molecular Weight | 413.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 8-[(6-Iodobenzo[d][1,3]dioxol-5-yl)thio]-9H-purin-6-amine (CAS 873436-89-6), a certified reference material (molecular formula C12H8IN5O2S, MW 413.19 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, iodine substitution, 8-[(6-Iodobenzo[d][1,3]dioxol-5-yl)thio]-9H-purin-6-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 413.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 8-[(6-Iodobenzo[d][1,3]dioxol-5-yl)thio]-9H-purin-6-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8IN5O2S |
| Molecular Weight | 413.19 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Iodobenzo Standards
- Benzyl 5-iodobenzo[b]thiophene-2-carboxylate (CAS 2497586-35-1)
- 8-((6-Iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine (CAS 873436-90-9)
- 2-Iodobenzo[e]pyrido[1,2-a][1,3]diazepin-6(11h)-imine (CAS 326617-79-2)
- Methyl 2-iodobenzo[d]thiazole-7-carboxylate (CAS 1379301-52-6)
- Methyl 4-iodobenzo[b]thiophene-2-carboxylate (CAS 146137-85-1)
- Methyl 5-iodobenzo[b]thiophene-2-carboxylate (CAS 146137-90-8)
- Methyl 3-iodobenzo[b]thiophene-2-carboxylate (CAS 683274-54-6)
- Ethyl 6-iodobenzo[d]isoxazole-3-carboxylate (CAS 1352395-67-5)
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Why CATO?
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