4-(2-(Difluoromethoxy)phenyl)-1H-pyrrole-3-carbonitrile CAS 87388-20-3
| CAS No. | 87388-20-3 |
| Molecular Formula | C12H8F2N2O |
| Molecular Weight | 234.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(2-(Difluoromethoxy)phenyl)-1H-pyrrole-3-carbonitrile (C12H8F2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-(2-(Difluoromethoxy)phenyl)-1H-pyrrole-3-carbonitrile (CAS 87388-20-3) is a high-purity analytical reference standard with the molecular formula C12H8F2N2O and a molecular weight of 234.20 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8F2N2O |
| Molecular Weight | 234.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 3',5'-Difluoro-[1,1'-biphenyl]-4-carboxylicacid (CAS 350682-84-7)
- 4-(2,3-Difluorophenyl)benzoic acid (CAS 505082-93-9)
- 3',5'-Difluoro-[1,1'-biphenyl]-2-carboxylicacid (CAS 886363-21-9)
- 4-(2,5-Difluorophenyl)benzoic acid (CAS 920294-24-2)
- 6-methoxy-1,2,3,4-tetrahydroquinoline-2,4-dione (CAS 1188436-95-4)
- 2-amino-1-(2,6-dichlorophenyl)ethan-1-ol hydrochloride (CAS 19062-17-0)
- 2-Amino-2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propanoic acid (CAS 1134434-42-6)
- Decitabine Impurity 46 (CAS CATO-C4X-113746)
- 2-(4-(4-(4-Chloro-1H-pyrazol-1-yl)butyl)piperazin-1-yl)pyrimidin-5-ol (CAS 159493-79-5)
- (4-Cyclopropyl-3-methylphenyl)boronic acid (CAS 2225177-95-5)
- (6-(Hydroxymethyl)pyridin-3-yl)boronic acid hydrochloride (CAS 1309980-30-0)
- 2-Chloro-3-methoxypyridine-4-carbaldehyde (CAS 905563-05-5)
- Nifuratel Impurity 14 (CAS 25294-71-7)
- Peptide 441 (CAS CATO-CPTD788441)
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