2,2-Bis(4-hydroxyphenyl)-2-[4-(trifluoromethyl)phenyl]trifluoroethane CAS 874438-52-5
| CAS No. | 874438-52-5 |
| Molecular Formula | C21H14F6O2 |
| Molecular Weight | 412.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,2-Bis(4-hydroxyphenyl)-2-[4-(trifluoromethyl)phenyl]trifluoroethane (CAS 874438-52-5), molecular formula C21H14F6O2 and molecular weight 412.33 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C21H14F6O2, 2,2-Bis(4-hydroxyphenyl)-2-[4-(trifluoromethyl)phenyl]trifluoroethane contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 412.33 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H14F6O2 |
| Molecular Weight | 412.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Bis Standards
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- 1-(4-Hydroxyphenyl)-2-phenyl-4-(2-(phenylthio)ethyl)pyrazolidine-3,5-dione (CAS 1174-98-7)
- (3AR)-5-(2-hydroxyphenyl)-3a-methyl-6-[3-(trifluoromethyl)benzoyl]-octahydropyrrolo[2,3-b]pyrrol-2-one (CAS 956964-50-4)
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Recommended Standards
- 1-(3,4-Dichlorobenzyl)-N'-(thiophene-2-carbonyl)piperidine-4-carbohydrazide (CAS 478078-41-0)
- 2,5-Dichloro-N-(5,6-dimethyl-1-propyl-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338423-78-2)
- Prucalopride Impurity 22 (CAS CATO-C4X-103822)
- 2,5-Dichloro-N-[5,6-dimethyl-1-(propan-2-yl)-1H-1,3-benzodiazol-4-yl]benzene-1-sulfonamide (CAS 338423-22-6)
- Adenosine-5-diphosphate trisodium salt (CAS 2092-65-1)
- 2-Bromo-6-iodo-4-methylaniline (CAS 289038-12-6)
- (3R,4R)-3-Cyclopropylpiperidin-4-amine dihydrochloride (CAS 444188-98-1)
- 1-Butyl-3-phenylimidazolidine (CAS 23954-02-1)
- 3-Chloro-5-hydroxypicolinonitrile (CAS 1262860-70-7)
- delta-Damascone (CAS 57378-68-4)
- Bicyclo[3.2.2]nonane-1,5-dicarboxylicacid (CAS 46368-93-8)
- Fmoc-Asp(CSY)-OH (CAS 2379679-90-8)
- L-Cysteine-D-penicillamine Disulfide (CAS 18840-45-4)
- Peptide Impurity 40 (CAS CATO-CPTD788840)
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