5-Bromo-n,n,4-trimethyl-1,3-thiazol-2-amine CAS 874508-77-7
| CAS No. | 874508-77-7 |
| Molecular Formula | C6H9BrN2S |
| Molecular Weight | 221.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Bromo-n,n,4-trimethyl-1,3-thiazol-2-amine (CAS 874508-77-7), molecular formula C6H9BrN2S and molecular weight 221.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromo-n,n,4-trimethyl-1,3-thiazol-2-amine (C6H9BrN2S) is characterized by a nitrile group, sulfur-containing functionality, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H9BrN2S |
| Molecular Weight | 221.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromo Standards
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- 2-Bromo-5-isobutyl-1,3,4-thiadiazole (CAS 1343796-64-4)
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- tert-Butyl (3-bromopyrazine-2-carbonyl)(tert-butoxy)carbamate (CAS 1956377-52-8)
- 2-Chloro-4-methylphenylboronic Acid (CAS 145349-62-8)
- n-(3-Bromo-5-fluorobenzyl)-2-chloroethan-1-amine (CAS 1507171-04-1)
- N-methyl-1-[2-(trifluoromethyl)phenyl]piperidin-4-amine (CAS 1096810-82-0)
- Freon #114 (CAS 76-14-2)
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