2-[1-(difluoromethyl)-1H-benzimidazol-2-yl]-1-thien-2-ylethanone CAS 874594-04-4
| CAS No. | 874594-04-4 |
| Molecular Formula | C14H10F2N2OS |
| Molecular Weight | 292.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-[1-(difluoromethyl)-1H-benzimidazol-2-yl]-1-thien-2-ylethanone (CAS 874594-04-4), molecular formula C14H10F2N2OS and molecular weight 292.30 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-[1-(difluoromethyl)-1H-benzimidazol-2-yl]-1-thien-2-ylethanone (C14H10F2N2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 292.30 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H10F2N2OS |
| Molecular Weight | 292.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- Cladribine EP Impurity E (CAS 1831121-84-6)
- 2-(4-methoxyphenoxymethyl)-1,3-thiazole-4-carbaldehyde (CAS 1082576-05-3)
- (5Z)-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-5-[(dimethylamino)methylidene]-1,3-diazinane-2,4,6-trione (CAS 303153-10-8)
- 2-(3-(Difluoromethoxy)-2-nitrobenzoyl)pyridine (CAS 1261587-39-6)
- 5-Chloro-1H-pyrrolo[2,3-b]pyridin-4-ol (CAS 1015610-47-5)
- Benserazide Impurity 9 (CAS CATO-C4X-14279)
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