(2E)-3-[2-(4-methoxyphenyl)-1,3-thiazol-4-yl]acrylic acid CAS 874623-16-2
| CAS No. | 874623-16-2 |
| Molecular Formula | C13H11NO3S |
| Molecular Weight | 261.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2E)-3-[2-(4-methoxyphenyl)-1,3-thiazol-4-yl]acrylic acid (C13H11NO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
(2E)-3-[2-(4-methoxyphenyl)-1,3-thiazol-4-yl]acrylic acid (CAS 874623-16-2) is a high-purity analytical reference standard with the molecular formula C13H11NO3S and a molecular weight of 261.30 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H11NO3S |
| Molecular Weight | 261.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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- 5-Iodothiophene-2-carbaldehyde (CAS 5370-19-4)
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- 4-(2-Isopropyl-5-methylphenoxy)aniline hydrochloride (CAS 1184979-25-6)
- 1-(Cyclopropylsulfonyl)piperazine hydrochloride (CAS 1057385-13-3)
- n-(4-Fluorobenzyl)pentan-3-amine (CAS 776296-35-6)
- 1-(Tert-butoxycarbonyl)-4-(4-chlorobenzyl)piperidine-4-carboxylic acid (CAS 170284-71-6)
- (1-(4-Methoxybenzyl)-1H-1,2,4-triazol-5-yl)methanamine (CAS 199014-16-9)
- 2-METHYL-5-(PIPERIDIN-4-YLOXY)BENZO[D]THIAZOLE (CAS 951623-91-9)
- (3S,4R)-1-Ethyl-3-fluoropiperidin-4-amine (CAS 1315545-97-1)
- D-[Ala]24-Semaglutide (CAS CATO-C4X-2226126)
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