2-(piperazin-1-ylmethyl)imidazo[1,2-a]pyridine CAS 874623-44-6
| CAS No. | 874623-44-6 |
| Molecular Formula | C12H16N4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(piperazin-1-ylmethyl)imidazo[1,2-a]pyridine (CAS 874623-44-6), molecular formula C12H16N4HCl and molecular weight 252.75 g/mol, is a CATO reference standard with documented purity and traceability.
2-(piperazin-1-ylmethyl)imidazo[1,2-a]pyridine (C12H16N4HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(piperazin-1-ylmethyl)imidazo[1,2-a]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16N4 2*HCl |
| Molecular Weight | 252.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related piperazin Standards
- 2-(3-(Piperazin-1-yl)propyl)isoindoline-1,3-dione (CAS 1000547-80-7)
- (4-Methyl-piperazin-1-yl)-(S)-pyrrolidin-2-yl-methanone (CAS 100158-68-7)
- (6-(Piperazin-1-yl)pyridin-3-yl)boronic acid (CAS 1003043-67-1)
- (2-(Piperazin-1-yl)pyridin-4-yl)boronic acid (CAS 1003043-70-6)
- N-(4-(Piperazin-1-ylsulfonyl)phenyl)acetamide (CAS 100318-71-6)
- Piperazin-1-yl(m-tolyl)methanone hydrochloride (CAS 100940-01-0)
- 2-(Piperazin-1-yl)phenol (CAS 1011-17-2)
- 2-phenyl-1-(piperazin-1-yl)butan-1-one (CAS 1016503-45-9)
Recommended Standards
- (8-(6-Chloropyridazin-3-yl)-1-oxa-4,8-diazaspiro[4.5]Decan-4-yl)(4-methoxyphenyl)methanone (CAS 339011-62-0)
- 6,7-Dimethoxy-1-(2-thienyl)-3,4-dihydroisoquinoline (CAS 88333-64-6)
- (2R,4s,5R)-5-aminospiro[3.3]Heptane-2-carboxylic acid (CAS 1682749-21-8)
- n-Ethyl-3-phenylpyrrolidine-1-carboxamide (CAS 1209587-47-2)
- 5-Bromo-N-(2,2-dimethylthietan-3-yl)pyrimidin-2-amine (CAS 1870232-41-9)
- 2-(3,3-Dimethylbut-1-yn-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 159087-41-9)
- 5-Methoxy-2-(((4-phenoxyphenyl)amino)methyl)phenol (CAS 763130-57-0)
- 5-Bromo-6-chloropicolinonitrile (CAS 1256823-65-0)
- 5-(3-Chloro-4-fluorophenyl)-3-methyl-3-(pyrimidin-5-ylmethyl)-1-(1H-1,2,4-triazol-3-yl)indolin-2-one (CAS 1141080-15-0)
- Liraglutide Impurity 21 TFA Salt (CAS CATO-C4X-199221)
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