2-Amino-3-bromo-5-(trifluoromethoxy)benzoic acid CAS 874774-41-1
| CAS No. | 874774-41-1 |
| Molecular Formula | C8H5BrF3NO3 |
| Molecular Weight | 300.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 300.03 g/mol gives 2-Amino-3-bromo-5-(trifluoromethoxy)benzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Amino-3-bromo-5-(trifluoromethoxy)benzoic acid (CAS 874774-41-1), molecular formula C8H5BrF3NO3 and molecular weight 300.03 g/mol, is a CATO reference standard with documented purity and traceability.
2-Amino-3-bromo-5-(trifluoromethoxy)benzoic acid (C8H5BrF3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5BrF3NO3 |
| Molecular Weight | 300.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- 2-Amino-4-bromo-5-(trifluoromethoxy)benzoic acid (CAS 1478188-07-6)
- 3-Amino-5-bromo-4-(trifluoromethoxy)benzoic acid (CAS 1805559-09-4)
- 4-Amino-3-bromo-5-(trifluoromethoxy)benzoic acid (CAS 453565-89-4)
- (6-Amino-4-(difluoromethyl)-5-iodopyridin-3-yl)methanol (CAS 1803672-85-6)
- (6-Amino-5-(difluoromethyl)-4-iodopyridin-3-yl)methanol (CAS 1805085-23-7)
- (4-Amino-3-(difluoromethyl)-5-iodopyridin-2-yl)methanol (CAS 1805214-94-1)
- (2-Amino-4-(difluoromethyl)-6-iodopyridin-3-yl)methanol (CAS 1806814-96-9)
- (2-Amino-6-(difluoromethyl)-5-iodopyridin-3-yl)methanol (CAS 1806815-11-1)
Recommended Standards
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- 1-BRomo-4-methoxy-5-nitro-2-trifluoromethyl-benzene (CAS 2092929-95-6)
- 2-Nitro-5-(trifluoromethoxy)benzyl bromide (CAS 875548-93-9)
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