2-((2-(Trifluoromethyl)quinolin-4-yl)thio)acetic acid CAS 874783-75-2
| CAS No. | 874783-75-2 |
| Molecular Formula | C12H8F3NO2S |
| Molecular Weight | 287.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((2-(Trifluoromethyl)quinolin-4-yl)thio)acetic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-((2-(Trifluoromethyl)quinolin-4-yl)thio)acetic acid (CAS 874783-75-2), a certified reference material (molecular formula C12H8F3NO2S, MW 287.26 g/mol) for analytical method development and quality control.
2-((2-(Trifluoromethyl)quinolin-4-yl)thio)acetic acid (C12H8F3NO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8F3NO2S |
| Molecular Weight | 287.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- Methyl 2-(3-(trifluoromethyl)phenyl)thiazole-5-carboxylate (CAS 1018975-69-3)
- 4-Methyl-2-(3-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid (CAS 144059-85-8)
- 4-Methyl-2-[4-(trifluoromethyl)phenyl]thiazole-5-carboxylic Acid (CAS 144059-86-9)
- 5-Methyl-2-(2-(trifluoromethyl)phenyl)thiazole-4-carboxylic acid (CAS 1549437-07-1)
- 2-[2-[4-(Trifluoromethyl)phenyl]thiazol-4-yl]acetic Acid (CAS 17969-63-0)
- 2-((6-(Trifluoromethyl)quinolin-4-yl)thio)acetic acid (CAS 874765-71-6)
- 2-((8-(Trifluoromethyl)quinolin-4-yl)thio)acetic acid (CAS 874606-36-7)
- 2-(3-(Trifluoromethyl)benzyl)thiazole-4-carboxylic acid (CAS 478030-66-9)
Recommended Standards
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