tert-Butyl((4-(chloromethyl)benzyl)oxy)dimethylsilane CAS 874883-18-8

Purity 97%+In StockPharmaceutical Standards
CAS No.874883-18-8
Molecular FormulaC14H23ClOSi
Molecular Weight270.87 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl((4-(chloromethyl)benzyl)oxy)dimethylsilane CAS 874883-18-8 chemical structure

Description

The occurrence of tert-Butyl((4-(chloromethyl)benzyl)oxy)dimethylsilane is closely related to a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

tert-Butyl((4-(chloromethyl)benzyl)oxy)dimethylsilane (CAS 874883-18-8) is a high-purity analytical reference standard with the molecular formula C14H23ClOSi and a molecular weight of 270.87 g/mol.

The molecular framework of tert-Butyl((4-(chloromethyl)benzyl)oxy)dimethylsilane (C14H23ClOSi) is characterized by a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H23ClOSi
Molecular Weight270.87 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1987
Halogen ContentCl-containing

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