5-(2,5-Dichlorophenyl)pyridin-2-amine CAS 875166-88-4

Description

The occurrence of 5-(2,5-Dichlorophenyl)pyridin-2-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-(2,5-Dichlorophenyl)pyridin-2-amine (CAS 875166-88-4) is a high-purity analytical reference standard with the molecular formula C11H8Cl2N2 and a molecular weight of 239.10 g/mol.

The molecular framework of 5-(2,5-Dichlorophenyl)pyridin-2-amine (C11H8Cl2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(2,5-Dichlorophenyl)pyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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