3-(4-Chloro-3-nitrophenyl)-6-(pyrrolidin-1-yl)-[1,2,4]triazolo[3,4-a]phthalazine CAS 87540-12-3
| CAS No. | 87540-12-3 |
| Molecular Formula | C19H15ClN6O2 |
| Molecular Weight | 394.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-(4-Chloro-3-nitrophenyl)-6-(pyrrolidin-1-yl)-[1,2,4]triazolo[3,4-a]phthalazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-(4-Chloro-3-nitrophenyl)-6-(pyrrolidin-1-yl)-[1,2,4]triazolo[3,4-a]phthalazine (CAS 87540-12-3), molecular formula C19H15ClN6O2 and molecular weight 394.81 g/mol, is a CATO reference standard with documented purity and traceability.
3-(4-Chloro-3-nitrophenyl)-6-(pyrrolidin-1-yl)-[1,2,4]triazolo[3,4-a]phthalazine (C19H15ClN6O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C19H15ClN6O2 |
| Molecular Weight | 394.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
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Recommended Standards
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- 1,4-Diamino-7-chloro-2-(4-methoxyphenoxy)anthracene-9,10-dione (CAS 88605-34-9)
- Cyclopropyl(3-(3-(furan-2-yl)-1,2,4-oxadiazol-5-yl)azetidin-1-yl)methanone (CAS 1428347-58-3)
- Methyl 3-(2,6-dimethylpiperidin-1-yl)propanoate (CAS 16490-92-9)
- 5-Methyl-N2-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidine-2,4-diamine (CAS 936092-52-3)
- tert-Butyl 2-(2-(4-bromophenyl)-5-oxomorpholino)acetate (CAS 2205414-64-6)
- 5-Hydroxypentanamide (CAS 29686-12-2)
- 1-[(4-Methylpiperazino)methyl]-1H-indole-2,3-dione 3-(N-phenylhydrazone) (CAS 338391-76-7)
- (4-Chlorophenyl)(1-hydroxycyclopentyl)methanone (CAS 1696839-44-7)
- 2-Ethyl-4-nitropyridine (CAS 101860-96-2)
- 2-(2-Benzhydrylquinuclidin-3-ylidene)-1-(2-methoxyphenyl)ethan-1-one (CAS 887109-77-5)
- β-Asp9-Tirzepatide (CAS CATO-CPTD788931)
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