2-Chloro-3-((2-hydroxypropyl)amino)naphthalene-1,4-dione CAS 875440-38-3
| CAS No. | 875440-38-3 |
| Molecular Formula | C13H12ClNO3 |
| Molecular Weight | 265.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-3-((2-hydroxypropyl)amino)naphthalene-1,4-dione is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Chloro-3-((2-hydroxypropyl)amino)naphthalene-1,4-dione (CAS 875440-38-3), a certified reference material (molecular formula C13H12ClNO3, MW 265.69 g/mol) for analytical method development and quality control.
Structurally, 2-Chloro-3-((2-hydroxypropyl)amino)naphthalene-1,4-dione (C13H12ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 265.69 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12ClNO3 |
| Molecular Weight | 265.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 2-(Chloro(phenyl)methyl)-4-(ethoxymethylene)oxazol-5(4H)-one (CAS 883813-77-2)
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- Potassium 2-(2-amino-5-iodophenyl)-2-oxoacetate (CAS 287393-80-0)
- 915923-70-5 (5,7-Dimethyl-2-oxo-2,3-dihydro-1H-indol-3-yl)acetic acid DTXSID60661656 (CAS 915923-70-5)
- 3,5,6-Triphenyl-2-thioxo-2,3-dihydrofuro[2,3-d]pyrimidin-4(1H)-one (CAS 875118-19-7)
- 2-((2-Chlorothiazol-5-yl)methoxy)benzonitrile (CAS 860787-01-5)
- 7-Nitro-2-oxo-2H-chromene-3-carboxylic acid (CAS 64962-93-2)
- (3-(Trifluoromethyl)pyridin-2-yl)methanamine hydrochloride (CAS 1187932-68-8)
- N-(((Propylthio)carbonyl)oxy)-2-(quinolin-8-yloxy)acetimidamide (CAS 88758-85-4)
- N-Ethyl-1H-imidazole-4-carboxamide (CAS 137480-25-2)
- 6-(Phenylsulfonyl)-3-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 692733-11-2)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
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