Fulvestrant Impurity 60 CAS 875573-69-6
| CAS No. | 875573-69-6 |
| Molecular Formula | C34H49F5O3S |
| Molecular Weight | 632.81 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Fulvestrant Impurity 60 (C34H49F5O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Fulvestrant Impurity 60 (CAS 875573-69-6), a pharmacopoeial impurity reference standard (molecular formula C34H49F5O3S, MW 632.81 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C34H49F5O3S |
| Molecular Weight | 632.81 g/mol |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fulvestrant Standards
- Fulvestrant Impurity 30 (CAS CATO-C4X-191730)
- Fulvestrant impurity 55 (CAS CATO-C4X-191755)
- Fulvestrant EP Impurity B (CAS 98008-06-1)
- Fulvestrant EP Impurity B (CAS CATO-C4X-191733)
- Fulvestrant 3-O-Methyl Impurity (CAS 1221256-46-7)
- Fulvestrant impurity 38 (CAS CATO-C4X-191738)
- Fulvestrant EP Impurity F (CAS CATO-C4X-19176)
- Fulvestrant Impurity 21 (CAS 261506-24-5)
Recommended Standards
- Phenyl 2-3-4-6-tetra-O-benzyl-β-D-thioglucopyranoside (CAS 38184-10-0)
- 104055-76-7 C36H56O9 Quinovic acid 3-O-alpha-L-rhamnopyranoside W2609 (CAS 104055-76-7)
- Phenyl 2-3-4-6-tetra-O-benzyl-β-D-thiogalactopyranoside (CAS 74801-29-9)
- Cinchonaglycoside A (CAS 107870-05-3)
- Phenylephrine Impurity 72 (CAS CATO-C4X-146772)
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- Methyl 2-(3,5-dibromo-2-hydroxyphenyl)acetate (CAS 76251-01-9)
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- 6-Amino-1,3-dimethyl-3,4-dihydro-1H-quinolin-2-one (CAS 1267973-48-7)
- 3-Bromo-1-trityl-1h-1,2,4-triazole (CAS 151899-63-7)
- Ponatinib Impurity 48 (CAS CATO-C4X-226948)
- Di-m-tolylphosphine oxide (CAS 145290-34-2)
- Xenopsin-Related Peptide 2 (XP-2) (H-9340.0005) (CAS 117442-29-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com