7-(Chloromethyl)-2-(methylthio)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one CAS 87572-21-2
| CAS No. | 87572-21-2 |
| Molecular Formula | C7H6ClN3OS2 |
| Molecular Weight | 247.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-(Chloromethyl)-2-(methylthio)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one (CAS 87572-21-2), molecular formula C7H6ClN3OS2 and molecular weight 247.73 g/mol, is a CATO reference standard with documented purity and traceability.
7-(Chloromethyl)-2-(methylthio)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one (C7H6ClN3OS2) contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-(Chloromethyl)-2-(methylthio)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6ClN3OS2 |
| Molecular Weight | 247.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Chloromethyl Standards
- 5-[4-(Chloromethyl)phenyl]-2-ethoxypyridine (CAS 1300640-25-8)
- 4-((Chloromethyl)sulfonyl)thiomorpholine 1,1-dioxide (CAS 1341763-94-7)
- 4-(Chloromethyl)-1-(2,4,5-trifluorophenyl)-1H-1,2,3-triazole (CAS 1340310-98-6)
- 4-(Chloromethyl)-1-(3,4,5-trifluorophenyl)-1H-1,2,3-triazole (CAS 1344062-41-4)
- 2-(Chloromethyl)-5-cyano-4-(difluoromethyl)-3-nitropyridine (CAS 1804690-80-9)
- 2-(Chloromethyl)-6-cyano-5-(difluoromethyl)-3-nitropyridine (CAS 1805973-39-0)
- 2-(Chloromethyl)-6-cyano-3-(difluoromethyl)-4-nitropyridine (CAS 1806957-56-1)
- 2-(Chloromethyl)-3-cyano-5-(difluoromethyl)-4-nitropyridine (CAS 1806979-86-1)
Recommended Standards
- 2-chloro-N4-(6-oxa-3-azabicyclo[3.1.1]heptan-3-yl)pyrimidine-4,5-diamine (CAS 2646592-58-5)
- N-((5-chlorothiophen-2-yl)methyl)-3-ethynylaniline (CAS 1020975-26-1)
- 5-Chloro-4-(((5-methyl-4h-1,2,4-triazol-3-yl)thio)methyl)-1,2,3-thiadiazole (CAS 1210454-99-1)
- 2-Chloro-N-(2-methoxyethyl)-N-(thiophen-2-ylmethyl)acetamide (CAS 103464-03-5)
- tert-Butyl ((7-bromo-4-oxo-3,4-dihydrophthalazin-1-yl)methyl)carbamate (CAS 2629316-12-5)
- N-Me-Phe-OBzl · p-tosylate (CAS 40298-25-7)
- 5-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxazolidin-2-one (CAS 2304631-32-9)
- CAS 2222690-89-1 (CAS 2222690-89-1)
- 6-Oxaspiro[4.5]Decan-9-amine (CAS 1343353-82-1)
- 4-chloro-5-iodo-7-(oxolan-3-yl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 262440-11-9)
- 2-(3-Benzyl-4-(tert-butoxycarbonyl)-2-oxopiperazin-1-yl)acetic acid (CAS 1260644-22-1)
- 6-(4-Methylbenzamido)hexanoic acid (CAS 78521-43-4)
- (S)-tert-Butyl 3-{[(3-bromophenyl)methyl]amino}piperidine-1-carboxylate (CAS 1338222-17-5)
- Insulin Degludec Impurity 7 (CAS CATO-C4X-21577)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com