5-Bromo-3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazolo[3,4-b]pyridine CAS 875781-19-4
| CAS No. | 875781-19-4 |
| Molecular Formula | C12H17BrIN3OSi |
| Molecular Weight | 454.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Bromo-3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazolo[3,4-b]pyridine (CAS 875781-19-4), molecular formula C12H17BrIN3OSi and molecular weight 454.18 g/mol, is a CATO reference standard with documented purity and traceability.
5-Bromo-3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazolo[3,4-b]pyridine (C12H17BrIN3OSi) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine/iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Bromo-3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazolo[3,4-b]pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H17BrIN3OSi |
| Molecular Weight | 454.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br/I-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 5-Bromo-3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazolo[3,4-c]pyridine (CAS 2097610-93-8)
- methyl 7-bromo-8-(1-hydroxy-1-methyl-ethyl)-2-oxo-selenopheno[3,2-h]chromene-3-carboxylate (CAS 2173398-07-5)
- N-(4-Bromo-3-methylphenyl)-5,7-dichlorothiazolo[4,5-d]pyrimidine-2-sulfonamide (CAS 1000573-10-3)
- N-(2-Bromo-4,6-difluorophenyl)-2-((4-ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618415-18-2)
- N-(2-Bromo-4,6-difluorophenyl)-2-((4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 573937-62-9)
- N-(2-Bromo-4,6-difluorophenyl)-2-((4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 577766-41-7)
- 6-Bromo-2-(4-iodophenyl)quinoline-4-carboxylic acid (CAS 364383-14-2)
- [[5-bromo-6-methoxy-1-[(4-oxo-2-thioxo-5-thiazolidinylidene)methyl]-2-naphthalenyl]oxy]-acetic Acid (CAS 123021-35-2)
Recommended Standards
- 4-tert-Butyl-N'-[(1E)-(3,5-dibromo-2-hydroxyphenyl)methylidene]benzohydrazide (CAS 328921-31-9)
- 4,5-Dibromo-1-(ethoxymethyl)-2-(2-ethoxynaphthalen-1-yl)-1H-imidazole (CAS 1001755-61-8)
- 1-Phenyl-2-(phenyl-lambda3-iodanylidene)-2-((trifluoromethyl)sulfonyl)ethan-1-one (CAS 1443036-49-4)
- 1-(5-Chloro-2-methylphenyl)-4-((2,4,5-trichlorophenyl)sulfonyl)piperazine (CAS 496054-75-2)
- 2-(5-Chloro-4-fluoropyridin-3-yl)ethan-1-amine (CAS 1393566-76-1)
- 1-(2-Fluorophenyl)cyclopentanecarbonitrile (CAS 214262-89-2)
- 2-Chloro-1-(3,4-dimethylphenyl)propan-1-one (CAS 735321-29-6)
- Pinaverium impurity 31 (CAS CATO-C4X-246731)
- (S)-Naproxen-d3 (CAS 1094102-82-5)
- 2-Methoxycyclohex-2-enone (CAS 23740-37-6)
- 2-Ethyl-5-methoxy-3-(4-methoxyphenyl)-1H-indole (CAS 91444-15-4)
- 3-(Methylsulfinyl)propanoic acid (CAS 14090-85-8)
- 6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl furan-2-carboxylate (CAS 877637-85-9)
- Tau Peptide (245-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 1428134-39-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com