6-Methyl-2-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one CAS 87591-75-1
| CAS No. | 87591-75-1 |
| Molecular Formula | C10H7F3N2O |
| Molecular Weight | 228.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-Methyl-2-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 87591-75-1) is a high-purity analytical reference standard with the molecular formula C10H7F3N2O and a molecular weight of 228.17 g/mol.
The molecular framework of 6-Methyl-2-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one (C10H7F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7F3N2O |
| Molecular Weight | 228.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
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- 3-(6-(Trifluoromethyl)pyridin-3-yl)-1H-pyrazol-5-amine (CAS 1040724-49-9)
- 1-[5-(trifluoromethyl)pyridin-2-yl]-1h-pyrazol-5-amine (CAS 107748-59-4)
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Recommended Standards
- 6-Methyl-2-(trifluoromethyl)-4H-chromen-4-one (CAS 579-00-0)
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- 6-Cyclopropyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile (CAS 861212-38-6)
- 7-Amino-4-(trifluoromethyl)quinolin-2(1H)-one (CAS 58721-76-9)
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- 4-{[11-(but-3-enoyloxy)undecyl]oxy}benzoic acid (CAS 141522-67-0)
- 3-(Diphenylphosphaneyl)propanenitrile (CAS 5032-65-5)
- 8-Bromo-1,3-dichloroisoquinoline (CAS 1936146-98-3)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
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