8-Bromocinnolin-4(1H)-one CAS 876-74-4
| CAS No. | 876-74-4 |
| Molecular Formula | C15H10O4 |
| Molecular Weight | 254.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Bromocinnolin-4(1H)-one.
8-Bromocinnolin-4(1H)-one (CAS 876-74-4), molecular formula C15H10O4 and molecular weight 254.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Bromocinnolin-4(1H)-one (C15H10O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-Bromocinnolin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H10O4 |
| Molecular Weight | 254.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Bromocinnolin Standards
- 1-(6-Bromocinnolin-3-yl)ethanone (CAS 1509900-01-9)
- 5-Bromocinnolin-4(1H)-one (CAS 1076-15-9)
- 7-Bromocinnolin-3-ol (CAS 1379338-09-6)
- 7-Bromocinnolin-4(1H)-one, 97% (CAS 1414956-67-4)
- 3-Bromocinnolin-4-ol (CAS 19419-09-1)
- 3-Bromocinnolin-4(1H)-one (CAS 335242-55-2)
- 6-Bromocinnolin-4(1H)-one, 97% (CAS 552330-87-7)
- 6-bromocinnolin-4-ol (CAS 876-88-0)
Recommended Standards
- 7-Methyl-4-oxo-4H-pyrimido[2,1-a]isoquinoline-3-carboxylic acid (CAS 95199-43-2)
- 9H-Fluorene-2,7-dicarboxylic acid (CAS 22980-67-2)
- 7-Hydroxy-3-phenoxy-4h-chromen-4-one (CAS 87891-60-9)
- 9-Oxo-xanthene-2-carboxylic Acid Methyl Ester (CAS 42946-50-9)
- 1-Methyl-2-(4-(naphthalen-2-yl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline (CAS 1234997-42-2)
- N-(3-Chloroquinoxalin-2-yl)-2-cyanoacetamide (CAS 554404-06-7)
- (2-(Ethoxydimethylsilyl)ethyl)diphenylphosphine (CAS 359859-29-3)
- 4-(Chloromethyl)-2-cyclopentyl-1,3-thiazole (CAS 774158-28-0)
- N-((2-methylfuran-3-yl)methyl)cyclobutanamine (CAS 1403567-23-6)
- 2-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde (CAS 17481-62-8)
- (2-Fluoropyridin-4-yl)methanamine dihydrochloride (CAS 667906-60-7)
- (R)-Methyl 4-((3R,5R,8R,9S,10S,13R,14S,17R)-3-acetoxy-10,13-dimethyl-12-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate (CAS 5143-55-5)
- Δ10-Tetrahydrocannabinol (CAS 7663-51-6)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
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