2,2,2-Trifluoro-1-(3-(hydroxymethyl)piperidin-1-yl)ethan-1-one CAS 876147-51-2
| CAS No. | 876147-51-2 |
| Molecular Formula | C8H12F3NO2 |
| Molecular Weight | 211.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2,2,2-Trifluoro-1-(3-(hydroxymethyl)piperidin-1-yl)ethan-1-one (CAS 876147-51-2), a certified reference material (molecular formula C8H12F3NO2, MW 211.18 g/mol) for analytical method development and quality control.
The molecular framework of 2,2,2-Trifluoro-1-(3-(hydroxymethyl)piperidin-1-yl)ethan-1-one (C8H12F3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H12F3NO2 |
| Molecular Weight | 211.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoro Standards
- 3,3,3-Trifluoro-1-(4-hydroxypiperidin-1-yl)propan-1-one (CAS 1155607-86-5)
- 2,2,2-Trifluoro-n-(4-hydroxycyclohexyl)acetamide (CAS 1183415-13-5)
- 2,2,2-Trifluoro-1-(4-(hydroxymethyl)piperidin-1-yl)ethan-1-one (CAS 156459-82-4)
- 2,2,2-Trifluoro-1-((3R,4R)-3-(hydroxymethyl)-4-methylpyrrolidin-1-yl)ethanone (CAS 277335-21-4)
- 2,2,2-Trifluoro-N-(2-hydroxycyclohexyl)acetamide (CAS 496941-90-3)
- 2,2,2-Trifluoro-N-(4-methylpiperazin-1-yl)acetamide (CAS 550302-21-1)
- 3,3,3-Trifluoro-2-(pyrrolidin-2-ylmethyl)propanoic acid (CAS 480438-82-2)
- 1,1,1-Trifluoro-3-(2-methylthiazol-4-yl)propan-2-ol (CAS 1484908-71-5)
Recommended Standards
- 2-(Ethynyltetrafluoro-l6-sulfaneyl)pyridine (CAS 2768781-42-4)
- 2-(2-(1-Amino-2-(1H-1,2,4-triazol-1-yl)ethylidene)hydrazinyl)-2-oxoacetamide (CAS 338405-25-7)
- 2-[3-(Trifluoromethyl)phenyl]pyrrole (CAS 41819-49-2)
- 1-Amino-6-(trifluoromethyl)naphthalene (CAS 39499-10-0)
- (2,2,2-Trifluoroethoxy)difluoroacetic Acid (CAS 152538-73-3)
- 4-(5,6-Difluoro-1h-1,3-benzodiazol-2-yl)aniline (CAS 1153806-57-5)
- 2-(Trichloromethyl)-3,4-dihydroquinazolin-4-one (CAS 5558-95-2)
- 1-(2-(Trifluoromethyl)thiazol-4-yl)ethanone (CAS 1541915-43-8)
- Benzo[b]selenophene-2-carbaldehyde (CAS 3541-39-7)
- 6-(2-Fluorophenyl)-6-oxohexanoic acid (CAS 56721-59-6)
- 4-Chloro-5-(isopentyloxy)pyridazin-3(2H)-one (CAS 1346697-49-1)
- (E)-2-(2-cyclopropylprop-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2246919-45-7)
- 9-Chlorospiro[benzo[c]fluorene-7,9'-fluorene] (CAS 1800333-59-8)
- D-Ser12-Semaglutide (CAS CATO-C4X-2226240)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com