tert-Butyl (4-iodo-2-methoxyphenyl)carbamate CAS 876346-94-0
| CAS No. | 876346-94-0 |
| Molecular Formula | C12H16INO3 |
| Molecular Weight | 349.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl (4-iodo-2-methoxyphenyl)carbamate.
tert-Butyl (4-iodo-2-methoxyphenyl)carbamate (CAS 876346-94-0), molecular formula C12H16INO3 and molecular weight 349.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of tert-Butyl (4-iodo-2-methoxyphenyl)carbamate (C12H16INO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16INO3 |
| Molecular Weight | 349.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-Butyl (4-(hydroxymethyl)-2-iodophenyl)carbamate (CAS 755034-87-8)
- Posaconazole impurity 211 (CAS CATO-C4X-1208211)
- Nifluridide (CAS 61444-62-0)
- Posaconazole impurity 212 (CAS CATO-C4X-1208212)
- Hydroxynorketamine (CAS 81395-70-2)
- (S)-2-Amino-N-((S)-1-benzyl-piperidin-3-yl)-N-ethyl-propionamide (CAS 1354007-36-5)
- 3-Bromo-2-methyl-pyridine-4-carbonitrile (CAS 51454-47-8)
- 2-Thioxooxazolidin-4-one (CAS 2346-24-9)
- 3-Acetamido-3-(4-fluorophenyl)propanoicacid (CAS 332052-58-1)
- 2-Fluoro-1-naphthalenecarboxaldehyde (CAS 82128-49-2)
- Hydroxyhopanone (CAS 1981-81-3)
- (2,2-Dimethylpropyl)[2-(4-methoxyphenyl)ethyl]amine (CAS 1226184-21-9)
- ethyl 4-oxo-6,7-dihydro-5H-pyrazolo[1,5-a]pyridine-5-carboxylate (CAS 2057509-08-5)
- D-Asp9-Tirzepatide (CAS CATO-CPTD788923)
Why CATO?
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