3,5-Dimethoxy-N-(4-(trifluoromethoxy)phenyl)benzamide CAS 876535-43-2
| CAS No. | 876535-43-2 |
| Molecular Formula | C16H14F3NO4 |
| Molecular Weight | 341.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3,5-Dimethoxy-N-(4-(trifluoromethoxy)phenyl)benzamide (CAS 876535-43-2), molecular formula C16H14F3NO4 and molecular weight 341.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3,5-Dimethoxy-N-(4-(trifluoromethoxy)phenyl)benzamide (C16H14F3NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H14F3NO4 |
| Molecular Weight | 341.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Dimethoxy Standards
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Recommended Standards
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- 5-Hydroxy-1H-indol-6-yl formate (CAS 143379-43-5)
- (S)-2-((tert-Butoxycarbonyl)amino)-5-(ethylamino)-5-oxopentanoic acid (CAS 210692-65-2)
- 5-Bromo-2-(1H-pyrazol-3-yl)phenol (CAS 114486-00-9)
- 1-Benzylpyridin-1-ium bromide (CAS 2589-31-3)
- [1-(2-thienyl)cyclopropyl]methanol (CAS 1447963-30-5)
- 6-(Hydroxymethyl)-4-methoxy-5-methyl Nicotinic Acid Methyl Ester (CAS 1251762-18-1)
- 1-([1,1'-Biphenyl]-4-yl)-3-((4-(sec-butyl)phenyl)amino)propan-1-one (CAS 882748-24-5)
- (1-(2-Chloro-6-fluorophenyl)cyclobutyl)methanamine (CAS 1039932-28-9)
- 1,2-Bis(4-ethylphenyl)ethyne (CAS 79135-69-6)
- [β-Asp]9-Semaglutide (CAS CATO-CPTD788605)
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