5-Ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid CAS 876708-62-2
| CAS No. | 876708-62-2 |
| Molecular Formula | C10H8F3N3O2 |
| Molecular Weight | 259.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 876708-62-2) is a high-purity analytical reference standard with the molecular formula C10H8F3N3O2 and a molecular weight of 259.18 g/mol.
Based on its molecular formula C10H8F3N3O2, 5-Ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 259.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8F3N3O2 |
| Molecular Weight | 259.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- Ethyl 7-(trifluoromethyl)imidazo[1,2-a]pyrimidine-6-carboxylate (CAS 1009662-98-9)
- Ethyl 7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylate (CAS 1018053-40-1)
- 3-(3-(Trifluoromethyl)-1H-pyrazolo[4,3-c]pyridin-1-yl)propanoic acid (CAS 1019115-17-3)
- 3-[4-(Trifluoromethyl)phenyl]-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 109888-65-5)
- Ethyl 7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylate (CAS 1119429-11-6)
- N-[3-(Trifluoromethyl)phenyl]maleamic acid (CAS 116401-44-6)
- Ethyl 7-(trifluoromethyl)pyrazolo-[1,5-a]pyrimidine-6-carboxylate (CAS 1245807-86-6)
- Ethyl 2-(trifluoromethyl)imidazo[1,2-a]pyrazine-6-carboxylate (CAS 1610666-96-0)
Recommended Standards
- 5-(Trifluoromethoxy)-1H-indole-2-carbohydrazide (CAS 685120-14-3)
- 5-Ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 876708-65-5)
- 4-Oxo-4-((3-(trifluoromethyl)phenyl)amino)but-2-enoic acid (CAS 296272-06-5)
- Ethyl 2-(trifluoromethyl)imidazo[1,2-a]pyrazine-3-carboxylate (CAS 420119-54-6)
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