4-(6-Fluoro-1H-benzo[d]imidazol-2-yl)butanoic acid CAS 876716-08-4
| CAS No. | 876716-08-4 |
| Molecular Formula | C11H11FN2O2 |
| Molecular Weight | 222.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(6-Fluoro-1H-benzo[d]imidazol-2-yl)butanoic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(6-Fluoro-1H-benzo[d]imidazol-2-yl)butanoic acid (CAS 876716-08-4), molecular formula C11H11FN2O2 and molecular weight 222.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(6-Fluoro-1H-benzo[d]imidazol-2-yl)butanoic acid (C11H11FN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(6-Fluoro-1H-benzo[d]imidazol-2-yl)butanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11FN2O2 |
| Molecular Weight | 222.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- Ethyl 2-(5-fluoro-1H-benzo[d]imidazol-2-yl)acetate (CAS 1196155-72-2)
- (1-(3-Fluoro-4-methoxyphenyl)-1H-1,2,3-triazol-4-yl)methanamine (CAS 1248988-93-3)
- Ethyl 6-fluoro-2-methylimidazo[1,2-a]pyridine-3-carboxylate (CAS 1417635-63-2)
- 1-(5-fluoro-2-methyl-phenyl)hexahydropyrimidine-2,4-dione (CAS 1508568-71-5)
- 1-(3-fluoro-5-methyl-phenyl)hexahydropyrimidine-2,4-dione (CAS 1514277-50-9)
- 1-(2-fluoro-4-methyl-phenyl)hexahydropyrimidine-2,4-dione (CAS 1515066-75-7)
- 2-Fluoro-3-(1-methyl-1h-benzo[d]imidazol-2-yl)propanoic acid (CAS 1517201-32-9)
- 1-(3-fluoro-4-methyl-phenyl)hexahydropyrimidine-2,4-dione (CAS 1520635-71-5)
Recommended Standards
- 4-(5-Nitrothiophen-2-yl)pyrimidin-2-amine (CAS 913322-71-1)
- 4-Oxo-2-sulfanyl-3,4-dihydroquinazoline-7-carboxylic acid (CAS 422277-16-5)
- 4-(5-Mercapto-1H-tetrazol-1-yl)benzoic acid (CAS 23249-95-8)
- 4-Oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-6-carboxylic acid (CAS 34330-02-4)
- Ethyl (4R,5R)-4,5-dimethyl-5-(trifluoromethyl)-3-(((trifluoromethyl)sulfonyl)oxy)-4,5-dihydrofuran-2-carboxylate (CAS 2649469-23-6)
- tert-Butyl 2-methoxy-5-oxopyrrolidine-1-carboxylate (CAS 1707379-66-5)
- 4,5,6,7-Tetrahydrobenzo[d]thiazol-2-amine hydrobromide (CAS 55895-83-5)
- 1-(4-Nonylphenyl)ethan-1-one (CAS 37593-05-8)
- (1S)-1-(adamantan-1-yl)ethan-1-amine hydrochloride (CAS 1005341-54-7)
- TERT-BUTYL 3-(PROPYLAMINO)PYRROLIDINE-1-CARBOXYLATE (CAS 887587-20-4)
- 6,7-Dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidin-3-ylacetic acid (CAS 343791-95-7)
- PCB-77-d6 & PCB-156-d3 Mix (CAS CATO-LCEM500806-HE)
- 3-(2-bromo-4-methylphenoxy)propanoic acid (CAS 926211-97-4)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
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