2,4,5,6-Tetrachloro-M-Xylene CAS 877-09-8
| CAS No. | 877-09-8 |
| Molecular Formula | C8H6Cl4 |
| Molecular Weight | 243.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,4,5,6-Tetrachloro-M-Xylene.
2,4,5,6-Tetrachloro-M-Xylene (CAS 877-09-8), molecular formula C8H6Cl4 and molecular weight 243.95 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to chlorine substitution, an aromatic ring system, 2,4,5,6-Tetrachloro-M-Xylene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 243.95 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,4,5,6-Tetrachloro-M-Xylene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6Cl4 |
| Molecular Weight | 243.95 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Tetrachloro Standards
- 2,3,5,6-Tetrachloro-p-xylene (CAS 877-10-1)
- 3,4,5,6-Tetrachloro-o-xylene (CAS 877-08-7)
- Tetrachloro-o-benzoquinone (CAS 2435-53-2)
- 1,2,3,5-Tetrachloro-4-methoxybenzene (CAS 938-22-7)
- 4,4,5,5-Tetrachloro-2,2-difluoro-1,3-dioxolane (CAS 87075-01-2)
- 2,3,5,6-Tetrachloro-1H-pyridine-4-thione (CAS 10351-06-1)
- 2,3,5,6-Tetrachloro-4-fluoropyridine (CAS 34415-32-2)
- 1,2,3,5-Tetrachloro-4-fluorobenzene (CAS 319-95-9)
Recommended Standards
- Montelukast Impurity 9 (CAS 30430-40-1)
- 3,4-Dibromohexane (CAS 16230-28-7)
- a,a,a',a'-Tetrachloro-o-xylene (CAS 25641-99-0)
- 1-Bromo-2-(bromomethyl)pentane (CAS 1781-52-8)
- 1-Butyl-1-methylpyrrolidinium Trifluoromethanesulfonate (CAS 367522-96-1)
- 1-Iodo-3-(propan-2-yl)imidazo[1,5-a]pyridine (CAS 1315366-01-8)
- (4-Chlorophenyl)(cyclopentyl)methanol (CAS 2205-00-7)
- 6-[(3,3,3-Trifluoro-2-hydroxypropyl)amino]-3,4-dihydro-2H-1,4-benzoxazin-3-one (CAS 861208-01-7)
- Propargyl-PEG14-alcohol (CAS 32199-97-6)
- (3R)-3-fluoropyrrolidin-2-one (CAS 1175052-20-6)
- 2-(Methylsulfanyl)-4,6-bis[(E)-2-phenylethenyl]nicotinonitrile (CAS 860649-66-7)
- 2-Ethyl-3,3-dimethylpentanoic acid (CAS 214692-25-8)
- (2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(3-methylpiperazin-1-yl)methanone hydrochloride (CAS 1353980-53-6)
- Insulin Glargine (CAS 160337-95-1)
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