1-(4-Bromo-2-fluorophenyl)urea CAS 877134-79-7

Purity 97%+In StockPharmaceutical Standards
CAS No.877134-79-7
Molecular FormulaC7H6BrFN2O
Molecular Weight233.04 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(4-Bromo-2-fluorophenyl)urea CAS 877134-79-7 chemical structure

Description

The occurrence of 1-(4-Bromo-2-fluorophenyl)urea is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-(4-Bromo-2-fluorophenyl)urea (CAS 877134-79-7) is a high-purity analytical reference standard with the molecular formula C7H6BrFN2O and a molecular weight of 233.04 g/mol.

The molecular framework of 1-(4-Bromo-2-fluorophenyl)urea (C7H6BrFN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(4-Bromo-2-fluorophenyl)urea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H6BrFN2O
Molecular Weight233.04 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF/Br-containing
Nitrogen Atoms2

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