4-Bromo-2-chloro-6-methylbenzonitrile CAS 877149-06-9
| CAS No. | 877149-06-9 |
| Molecular Formula | C8H5BrClN |
| Molecular Weight | 230.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Bromo-2-chloro-6-methylbenzonitrile (CAS 877149-06-9) is a high-purity analytical reference standard with the molecular formula C8H5BrClN and a molecular weight of 230.49 g/mol.
4-Bromo-2-chloro-6-methylbenzonitrile (C8H5BrClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5BrClN |
| Molecular Weight | 230.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-(3-Bromo-5-chlorophenyl)acetonitrile (CAS 1056454-88-6)
- 2-(5-Bromo-2-chlorophenyl)acetonitrile (CAS 1057216-52-0)
- 3-Bromo-6-chloro-1H-indole (CAS 1094641-40-3)
- 3-Bromo-4-chloro-1H-indole (CAS 1181332-74-0)
- 4-Bromo-5-chloro-1H-indole (CAS 1191028-48-4)
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- 5-Bromo-6-chloroindole (CAS 122531-09-3)
- 4-Bromo-5-chloro-2-methylbenzonitrile (CAS 1228376-18-8)
Recommended Standards
- 4-(Bromomethyl)-3-chlorobenzonitrile (CAS 21924-83-4)
- 4-bromo-3-(chloromethyl)benzonitrile (CAS 853027-80-2)
- 4-(Bromomethyl)-2-chlorobenzonitrile (CAS 83311-25-5)
- 4-Bromo-6-chloro-1H-indole (CAS 885519-23-3)
- 2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanol (CAS 306298-23-7)
- 5-Amino-3-bromo-N-(3-chloro-4-fluorophenyl)-1-methyl-1H-pyrazole-4-carboxamide (CAS 2417111-98-7)
- 8,8-Difluoro-1-azaspiro[4.5]Decane-2-carboxylic acid (CAS 2387594-62-7)
- 3-[(2-amino-4-chlorophenyl)sulfanyl]-1-methylpyrrolidin-2-one (CAS 1339603-01-8)
- 2,3,6-Trichloro-4-(trifluoromethyl)pyridine (CAS 81565-20-0)
- Benzo[c][1,2,5]oxadiazole-4-carbonyl chloride (CAS 111595-71-2)
- 2-(3-Amino-4-bromophenyl)propan-2-ol (CAS 1890327-36-2)
- 3H-Pyrazol-3-ol (CAS 145091-86-7)
- 3-[Ethoxy(ethyl)phosphoryl]prop-2-enoic acid (CAS 1086275-08-2)
- Peptide 439 (CAS CATO-CPTD788439)
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