2-Chloro-1-(isoxazolidin-2-yl)propan-1-one CAS 87757-22-0

Purity 97%+In StockPharmaceutical Standards
CAS No.87757-22-0
Molecular FormulaC6H10ClNO2
Molecular Weight163.60 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-1-(isoxazolidin-2-yl)propan-1-one CAS 87757-22-0 chemical structure

Description

The occurrence of 2-Chloro-1-(isoxazolidin-2-yl)propan-1-one is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2-Chloro-1-(isoxazolidin-2-yl)propan-1-one (CAS 87757-22-0), a certified reference material (molecular formula C6H10ClNO2, MW 163.60 g/mol) for analytical method development and quality control.

The molecular framework of 2-Chloro-1-(isoxazolidin-2-yl)propan-1-one (C6H10ClNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H10ClNO2
Molecular Weight163.60 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1982
Halogen ContentCl-containing
Nitrogen Atoms1

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