Darifenacin Impurity 1 CAS 87776-76-9
| CAS No. | 87776-76-9 |
| Molecular Formula | C10H12O2 |
| Molecular Weight | 164.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Darifenacin Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Darifenacin Impurity 1 (CAS 87776-76-9, C10H12O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Darifenacin Impurity 1 (C10H12O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C10H12O2 |
| Molecular Weight | 164.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
Related Darifenacin Standards
- Darifenacin Impurity 8 (CAS 87776-69-9)
- Darifenacin Impurity 9 (CAS 142935-60-2)
- Darifenacin 5-Carboxymethyl Impurity (CAS 69999-16-2)
- Darifenacin Vinylbenzofuran Impurity (CAS 633335-98-5)
- Darifenacin USP Related Compound G (CAS 127264-14-6)
- Darifenacin 7-Bromoethyl Impurity (CAS 1598271-92-1)
- Darifenacin KSM-II B(1-tosyl-(3S)-hydrox (CAS 133034-00-1)
- Darifenacin Morpholine Amide Impurity (CAS 97483-11-9)
Recommended Standards
- Dobutamine EP Impurity B (CAS 5471-51-2)
- Primidone EP Impurity E (CAS 90-27-7)
- 1-Methoxy-2-(2-propen-1-yloxy)benzene (CAS 4125-43-3)
- Nintedanib Impurity 47 (CAS 119-63-1)
- Levonorgestrel EP Impurity G (CAS 87585-03-3)
- Floxuridine Impurity 1 (CAS 3094-09-0)
- Prilocaine EP Impurity E (CAS 744961-76-0)
- Thiophene-3-carboxylic acid 1,1-dioxide (CAS 1858240-97-7)
- Goserelin EP Impurity K (CAS 1926163-83-8)
- n-(3-Cyanophenyl)-2,4-dimethylthiazole-5-carboxamide (CAS 892365-22-9)
- 2-(Difluoromethyl)-5-iodo-3-nitropyridine-4-carboxamide (CAS 1806954-12-0)
- [3-(Trifluoromethyl)phenyl](2,4,6-trimethylphenyl)iodonium Trifluoromethanesulfonate (CAS 1204518-08-0)
- 4-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-N-methylaniline (CAS 153729-53-4)
- C-Peptide (human) (CAS 33017-11-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com