1H-Imidazole-2-sulfonyl chloride hydrochloride CAS 877861-76-2

Description

The occurrence of 1H-Imidazole-2-sulfonyl chloride hydrochloride is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1H-Imidazole-2-sulfonyl chloride hydrochloride (CAS 877861-76-2), molecular formula C3H3ClN2O2SHCl and molecular weight 203.04 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1H-Imidazole-2-sulfonyl chloride hydrochloride (C3H3ClN2O2SHCl) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1H-Imidazole-2-sulfonyl chloride hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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