Acotiamide Impurity 37 CAS 877997-99-4
| CAS No. | 877997-99-4 |
| Molecular Formula | C14H14N2O6S |
| Molecular Weight | 338.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Acotiamide Impurity 37 (CAS 877997-99-4, C14H14N2O6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Acotiamide Impurity 37 (C14H14N2O6S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H14N2O6S |
| Molecular Weight | 338.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Acotiamide Standards
- Acotiamide Impurity 10 (CAS CATO-C4X-111410)
- Acotiamide Impurity 20 (CAS CATO-C4X-111420)
- Acotiamide Impurity 46 (CAS CATO-C4X-111446)
- Acotiamide Impurity 1 (CAS CATO-C4X-11141)
- Acotiamide Impurity 3 (CAS 1824734-16-8)
- Acotiamide Impurity 18 (CAS CATO-C4X-111418)
- Acotiamide Impurity 24 (CAS 185106-05-2)
- Acotiamide Impurity 19 (CAS CATO-C4X-111419)
Recommended Standards
- 3-Chloro-4,5-dibromobenzotrifluoride (CAS 1000577-74-1)
- 799-55-3 BIS(4-METHOXYPHENYL)PHENYLPHOSPHINE OXIDE DTXSID00404605 (CAS 799-55-3)
- Methyl 7-[(4-fluorophenyl)methyl]-5,8-dioxo-hexahydro-1H-[1,3]thiazolo[3,4-a]pyrazine-3-carboxylate (CAS 1007933-01-8)
- N-(2,5-Dimethoxyphenyl)-3-nitrobenzenesulfonamide (CAS 333440-84-9)
- Upadacitinib Impurity 127 (CAS CATO-C4X-2405127)
- Brivaracetam Impurity 33 (CAS CATO-C4X-200733)
- Quetiapine Impurity 54 (CAS 4171-83-9)
- Moxisylyte Hydrochloride (CAS 964-52-3)
- 2,6-Dichloro-3-methylisonicotinonitrile (CAS 862172-61-0)
- Methyl 3,5-dibromo-4-oxopentanoate (CAS 140663-07-6)
- 1-(5-Bromopyridin-2-yl)piperidine-4-carboxylic acid (CAS 954570-88-8)
- Histone H3 (21-44) trifluoroacetate salt (CAS 1373516-71-2)
- 3-[(2,2-dimethoxyethyl)amino]propan-1-ol (CAS 1339694-60-8)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com