Methyl 1-(3-bromopyridin-2-yl)piperidine-4-carboxylate CAS 878207-87-5
| CAS No. | 878207-87-5 |
| Molecular Formula | C12H15BrN2O2 |
| Molecular Weight | 299.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 1-(3-bromopyridin-2-yl)piperidine-4-carboxylate (CAS 878207-87-5) is a high-purity analytical reference standard with the molecular formula C12H15BrN2O2 and a molecular weight of 299.16 g/mol.
The molecular framework of Methyl 1-(3-bromopyridin-2-yl)piperidine-4-carboxylate (C12H15BrN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Methyl 1-(3-bromopyridin-2-yl)piperidine-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15BrN2O2 |
| Molecular Weight | 299.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 1-[(6-Bromopyridin-2-yl)methyl]-piperidine-4-carboxylic acid 1215838-59-7 (CAS 1215838-59-7)
- 8-(3-Bromopyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]Decane (CAS 1217194-56-3)
- methyl 1-(5-bromopyridin-2-yl)piperidine-4-carboxylate (CAS 1289027-00-4)
- 8-(5-Bromopyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]Decane (CAS 501954-42-3)
- 2-(2-bromopyridin-3-yloxy)-5-(chloromethyl)pyridine (CAS 1065484-75-4)
- (6-Bromopyridin-3-yl)(2-chlorophenyl)methanol (CAS 2230490-53-4)
- 1-((5-Bromopyridin-2-yl)methyl)-4-propylpiperazine (CAS 1333689-24-9)
- 1-(5-Bromopyridin-2-yl)-4-(2-methoxyethyl)piperazine (CAS 1281000-76-7)
Recommended Standards
- Methyl (S)-3-(6-bromochroman-2-yl)propanoate (CAS 2088284-58-4)
- Methyl 4-(3-bromophenyl)tetrahydro-2H-pyran-4-carboxylate (CAS 944924-92-9)
- Methyl (R)-3-(6-bromochroman-2-yl)propanoate (CAS 2088284-57-3)
- Methyl 4-(4-Bromophenyl)-2,2-dimethyl-4-oxobutanoate (CAS 791593-73-2)
- Methyl 3-bromo-4-(dimethylamino)benzoate (CAS 71695-21-1)
- (1R,6R)-7-Azabicyclo[4.2.0]octane (CAS 1807941-12-3)
- 4-{[2-(propan-2-yl)phenyl]amino}benzoic acid (CAS 1522104-76-2)
- 2,2-Difluoro-2-(1-hydroxy-4,4-dimethylcyclohexyl)acetic acid (CAS 681240-24-4)
- 1-(1-propyl-1H-pyrazol-4-yl)ethanamine,2HCl (CAS 1432027-55-8)
- 1-Boc-5-fluoroindole-2-boronic Acid (CAS 352359-23-0)
- 1-bromo-3-cyclobutylpropan-2-one (CAS 1698354-18-5)
- N1-(1-Benzylpyrrolidin-3-yl)-N1-isopropylethane-1,2-diamine (CAS 1353974-19-2)
- 2-Hydroxy-7-methyl-4h-pyrido[1,2-a]pyrimidin-4-one (CAS 306281-27-6)
- a-Bag Cell Peptide (1-8) (CAS 87549-53-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com