n-[4-(2-amino-1,3-thiazol-4-yl)-3-fluorophenyl]acetamide CAS 878218-34-9
| CAS No. | 878218-34-9 |
| Molecular Formula | C11H10FN3OS |
| Molecular Weight | 251.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
n-[4-(2-amino-1,3-thiazol-4-yl)-3-fluorophenyl]acetamide (CAS 878218-34-9), molecular formula C11H10FN3OS and molecular weight 251.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of n-[4-(2-amino-1,3-thiazol-4-yl)-3-fluorophenyl]acetamide (C11H10FN3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), n-[4-(2-amino-1,3-thiazol-4-yl)-3-fluorophenyl]acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10FN3OS |
| Molecular Weight | 251.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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- 4-Cyclopropoxy-N,N,5-trimethylpicolinamide (CAS 1243403-46-4)
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- Methyl 2-methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carboxylate (CAS 179950-77-7)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
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