2-[6-(4-fluorophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetic acid CAS 878259-69-9
| CAS No. | 878259-69-9 |
| Molecular Formula | C13H9FN2O2S |
| Molecular Weight | 276.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-[6-(4-fluorophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetic acid (CAS 878259-69-9) is a high-purity analytical reference standard with the molecular formula C13H9FN2O2S and a molecular weight of 276.29 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 2-[6-(4-fluorophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 276.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-[6-(4-fluorophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9FN2O2S |
| Molecular Weight | 276.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related fluorophenyl Standards
- 6-(3-Fluorophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxylic acid (CAS 1131580-14-7)
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- 1-(4-Fluorophenyl)-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (CAS 325721-14-0)
- 6-(4-Fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxylic acid (CAS 951908-85-3)
- 3-(4-fluorophenyl)-1-(2-naphthyl)prop-2-en-1-one (CAS 104765-79-9)
- 1-(2-Fluorophenyl)-3-(naphthalen-2-yl)prop-2-en-1-one (CAS 867294-23-3)
- 4-(2-Fluorophenyl)-4-(4-fluorophenyl)butanoic acid (CAS 132712-53-9)
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Recommended Standards
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- 2-Acetamido-3-(5-methoxy-1H-indol-3-yl)propanoic acid (CAS 43167-40-4)
- (7-Methyl-7H-pyrrolo[2,3-b]pyridin-3-yl)methanamine dihydrochloride (CAS 1881296-03-2)
- 2-(1,5-Dimethyl-4-phenoxy-1H-pyrazol-3-yl)-5-ethoxyphenol (CAS 394237-84-4)
- 3-Chloro-5-[(4-methylphenyl)methanesulfonyl]-1,2,4-thiadiazole (CAS 494763-26-7)
- Diethyl 5-amino-3-(pyridin-4-yl)-[1,2,4]triazolo[4,3-a]pyridine-6,8-dicarboxylate (CAS 135449-28-4)
- 2-(2-Methyl-1H-benzo[d]imidazol-1-yl)propanoic acid (CAS 753489-92-8)
- CAS 2755648-48-5 (CAS 2755648-48-5)
- (1S,3s)-3-methoxy-3-(trifluoromethyl)cyclobutan-1-amine (CAS 2378502-01-1)
- tert-Butyl 8-chloro-3,4,4a,5-tetrahydro-1H-pyrido[4,3-b]indole-2(9bH)-carboxylate (CAS 885272-52-6)
- 4-Bromo-5-chloro-2,3-dihydro-1H-indene (CAS 2438334-58-6)
- C-Peptide 1 (rat) (CAS 41475-27-8)
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