tert-Butyl 5-methylspiro[indoline-3,4'-piperidine]-1-carboxylate CAS 878376-82-0
| CAS No. | 878376-82-0 |
| Molecular Formula | C18H26N2O2 |
| Molecular Weight | 302.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-Butyl 5-methylspiro[indoline-3,4'-piperidine]-1-carboxylate (CAS 878376-82-0) is a high-purity analytical reference standard with the molecular formula C18H26N2O2 and a molecular weight of 302.41 g/mol.
tert-Butyl 5-methylspiro[indoline-3,4'-piperidine]-1-carboxylate (C18H26N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures tert-Butyl 5-methylspiro[indoline-3,4'-piperidine]-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H26N2O2 |
| Molecular Weight | 302.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl 4-(indolin-3-yl)piperidine-1-carboxylate (CAS 923136-79-2)
- tert-Butyl 6'-amino-1',1'-dimethyl-1'H-spiro[cyclopropane-1,4'-isoquinoline]-2'(3'H)-carboxylate (CAS 2387130-69-8)
- tert-Butyl 4-(2,3-dihydro-1H-indol-1-yl)piperidine-1-carboxylate (CAS 400828-91-3)
- tert-Butyl 7-benzyl-4,7-diazaspiro[2.5]octane-4-carboxylate (CAS 674792-03-1)
- 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-carbonitrile (CAS 65143-08-0)
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Why CATO?
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